© Copyright 2026 American Medical Association. All rights reserved.
The thymus is a small, vital organ located in the upper chest, beneath the sternum, and extends from the base of the throat to the front of the heart. It plays a crucial role during fetal development and childhood by producing and aiding in the maturation of T-lymphocytes, which are essential for the immune system. The thymus reaches its maximum size during puberty, after which it gradually decreases in size and is eventually replaced by fatty tissue in adulthood. A thymectomy, which can be either partial or total, is performed using a transcervical approach and is classified as a separate procedure. This surgical intervention is indicated for various conditions, including non-metastatic thymoma, thymic carcinoid, thymic carcinoma, and myasthenia gravis. The procedure involves making an incision above the sternal notch, allowing access to the thymus for removal while ensuring minimal disruption to surrounding structures.
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