CPT® Code 64400

The CPT® Code 64400 refers to the injection of anesthetic agents and/or steroids into the trigeminal nerve, which is a critical nerve responsible for sensation in the face and motor functions such as biting and chewing. This procedure is commonly known as a nerve block and can serve both diagnostic and therapeutic purposes. It is important to note that this code is reported once for each branch of the trigeminal nerve that is injected, which includes the ophthalmic, maxillary, and mandibular branches, regardless of how many times the injection is performed. Trigeminal neuralgia, a condition characterized by severe, shock-like stabbing pain, is the most prevalent indication for this type of nerve block. The procedure can be performed using either an intraoral or transcutaneous approach, depending on which branch of the trigeminal nerve is targeted. During the procedure, a needle is carefully introduced into the trigeminal nerve at the base of the skull or along its branches, and an anesthetic agent, such as glycol, is injected. Following the injection, the patient is typically asked to evaluate the level of pain relief experienced. This procedure is distinct from other nerve injections, such as the injection of the greater occipital nerve, which is addressed under CPT® Code 64405 and targets a different area of the body related to occipital neuralgia.