© Copyright 2026 American Medical Association. All rights reserved.
Chemodenervation of the salivary glands, specifically the parotid and submandibular glands, is a medical procedure aimed at reducing excessive salivation, a condition known as sialorrhea. This condition can significantly impact the quality of life for individuals suffering from various neurological disorders, including cerebral palsy, Parkinson's disease, and the residual effects following a cerebrovascular accident, commonly referred to as a stroke. The procedure involves the use of Type A botulinum toxin, which is injected directly into the targeted glands. The injections work by blocking the nerve signals that stimulate saliva production, thereby alleviating the symptoms associated with sialorrhea. To ensure precision in targeting the glands, imaging guidance may be employed as necessary. The procedure may require multiple injections in each gland to achieve the desired effect of denervation, ultimately helping to manage the symptoms of excessive salivation effectively.
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