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Official Description

Destruction by neurolytic agent, genicular nerve branches including imaging guidance, when performed

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The procedure described by CPT® Code 64624 involves the destruction of the genicular nerve branches, which are responsible for transmitting pain signals from the knee. This procedure is performed using a neurolytic agent, which can be a chemical substance or a method known as radiofrequency ablation (RFA). The genicular nerve branches targeted in this procedure include the superolateral, superomedial, and inferomedial branches. The primary aim of this intervention is to alleviate chronic knee pain, particularly pain associated with conditions such as osteoarthritis, and to enhance the patient's mobility. Chemical neurolysis is achieved through the injection of agents like phenol, alcohol, or glycerol, which effectively destroy the nerve fibers and provide an anesthetic effect on the smaller nerve branches. Alternatively, radiofrequency ablation utilizes heat generated by a high-frequency electrical current to induce coagulative necrosis, thereby destroying the nerve tissue. Prior to the procedure, the skin at the injection site is prepared, and local anesthesia is administered to minimize discomfort. Depending on the patient's needs, intravenous sedation may also be employed. The procedure typically involves the use of fluoroscopic imaging guidance to accurately position the needle into the target area, ensuring that the neurolytic agent is delivered precisely to the intended nerve branches.

© Copyright 2026 Coding Ahead. All rights reserved.

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