Coding Ahead
CasePilot
Medical Coding Assistant
CaseConsultant
Instant Email Coding Consultant
Case2Code
Search and Code Lookup Tool
CareerCenter
Medical Coding Job Board
Log in Register free account
0 code page views remaining. Guest accounts are limited to 1 page view. Register free account to get 5 more views.
Log in Register free account

Official Description

Destruction by neurolytic agent; other peripheral nerve or branch

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The procedure described by CPT® Code 64640 involves the destruction of a peripheral nerve or its branch using a neurolytic agent. This intervention is primarily aimed at alleviating chronic pain that may not respond to conventional treatments. The destruction can be achieved through various techniques, including the injection of a chemical neurolytic agent or the application of thermal, electrical, or radiofrequency methods. Among these, radiofrequency destruction has emerged as the most prevalent technique due to its effectiveness in targeting specific nerve pathways associated with pain syndromes. The process begins with the careful introduction of an electrode needle through the skin, which is then advanced toward the nerve tissue intended for treatment. This step is crucial as it allows for precise motor and sensory testing to confirm the correct positioning of the needle at the nerve responsible for the patient's pain. Once the appropriate nerve pathway is identified, the destruction of the nerve is performed. If a chemical neurolytic agent is utilized, it is injected along the nerve pathway to achieve the desired effect. Common neurolytic agents include phenol, ethyl alcohol, glycerol, ammonium salt compounds, and hypertonic or hypotonic solutions. Alternatively, thermal or electrical modalities involve the use of a probe or needle that generates heat to destroy the nerve tissue. In the case of radiofrequency nerve destruction, the electrode needle is positioned accurately, and the radiofrequency device is activated to produce an electric current that generates heat at the electrode's tip, effectively destroying the targeted nerve tissue. This procedure is coded under 64640 when there is no more specific code available for the destruction of the peripheral nerve or branch.

© Copyright 2026 Coding Ahead. All rights reserved.

CasePilot
Have a question about CPT® Code 64640?

Get instant expert-level answers from CasePilot, our coding assistant.

Register to view content

Create a free account to unlock this content

Register to view content

Create a free account to unlock this content

Register to view content

Create a free account to unlock this content

Register to view content

Create a free account to unlock this content

Register to view content

Create a free account to unlock this content

Register to view content

Create a free account to unlock this content

CasePilot

Get instant expert-level medical coding assistance.

Ask about:
CPT Codes Guidelines Modifiers Crosswalks NCCI Edits Compliance Medicare Coverage
Example: "What is CPT code 99213?" or "Guidelines for E/M services"