CPT® Code 64644

Chemodenervation is a medical procedure aimed at alleviating involuntary muscle contractions or spasms that can occur in various conditions such as dystonia, cerebral palsy, or multiple sclerosis. This procedure specifically targets the muscles of one extremity, which may be affected by these involuntary movements. The technique involves the injection of botulinum toxin, either type A or B, directly into the affected muscles. The primary mechanism of action is the temporary paralysis of the muscle, achieved by blocking the release of acetylcholine at the peripheral nerve endings. This interruption in neuromuscular transmission effectively reduces the muscle's ability to contract, thereby providing relief from spasms. Prior to the procedure, the specific muscles to be injected are identified through methods such as electromyography or a physical examination, which includes palpating the muscles and observing the areas of spasm. Once the targeted muscles are determined, the extremity is prepared for the injections, and the botulinum toxin is administered at carefully selected sites to ensure effective denervation. For coding purposes, CPT® Code 64644 is used when five or more muscles in one extremity are treated, while CPT® Code 64645 is designated for five or more muscles in each additional extremity.