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Official Description

Excision of neurofibroma or neurolemmoma; cutaneous nerve

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

Neurofibromas are benign tumors that develop from nerve fibers, specifically arising from the proliferation of Schwann cells, which are essential for the formation of the myelin sheath that insulates nerve fibers. These tumors are among the most prevalent types of peripheral nerve tumors and can manifest as solitary growths or, more commonly, in multiples as part of a genetic condition known as neurofibromatosis. Neurofibromatosis is characterized by a wide spectrum of severity, ranging from mild cases with few tumors to severe instances where numerous tumors can lead to significant health complications. While neurofibromas are generally non-cancerous, certain types, such as plexiform neurofibromas, have the potential to undergo malignant transformation, posing a greater risk to the patient. Plexiform neurofibromas are distinguished by their large size and their involvement of a long segment of a nerve or multiple nerves. On the other hand, neurolemmomas, also referred to as schwannomas, are tumors that arise from the outermost sheath of Schwann cells, known as the neurolemma. The procedure described by CPT® Code 64788 involves the excision of a cutaneous nerve neurofibroma or neurolemmoma. This surgical intervention begins with making a skin incision directly over the tumor site, followed by careful dissection to expose the tumor. The tumor is then meticulously separated from the surrounding tissue and excised, after which the incision is closed. This procedure is critical for alleviating symptoms associated with these tumors and preventing potential complications related to their growth.

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