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Official Description

Keratoplasty (corneal transplant); penetrating (in aphakia)

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

Keratoplasty, specifically referred to as penetrating keratoplasty in the context of aphakia, is a surgical procedure aimed at enhancing visual acuity by replacing the damaged or diseased corneal tissue with healthy corneal tissue obtained from a donor. This procedure is particularly indicated for patients who have experienced significant corneal opacification or other corneal pathologies that impair vision. During the operation, the surgeon utilizes an operating microscope to achieve a high level of precision and visualization of the eye's structures. A specialized instrument known as a trephine is employed to excise a circular segment of the patient's cornea, which is then replaced with a similarly shaped piece of donor cornea, ensuring that the epithelial side is oriented correctly towards the recipient's eye. Following the placement of the donor tissue, it is secured in position using sutures. To facilitate healing and prevent infection, antibiotic eye drops may be administered, and the eye is typically protected with a patch or shield post-operatively. This code, CPT® 65750, specifically encompasses penetrating keratoplasty performed in cases of corneal edema that may arise following cataract extraction, distinguishing it from other related procedures such as CPT® 65755, which pertains to cases involving a pseudophakia intraocular lens.

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