CPT® Code 68100

The procedure described by CPT® Code 68100 refers to a biopsy of the conjunctiva, which is a critical diagnostic tool in ophthalmology. The conjunctiva is a thin, transparent mucous membrane that covers the anterior surface of the eyeball, known as the bulbar conjunctiva, and the inner surface of the eyelids, referred to as the palpebral conjunctiva. This biopsy is typically indicated when there is a visible lesion on the conjunctiva or in cases of persistent conjunctivitis that does not respond to standard treatments. Additionally, a conjunctival biopsy can be instrumental in diagnosing various systemic diseases, including sarcoidosis, ocular pemphigoid, Stevens-Johnson syndrome, and amyloidosis. During the procedure, anesthetic eye drops are administered to ensure patient comfort by numbing the eye. The physician then uses forceps to grasp the conjunctiva and excises a small tissue sample with scissors. This tissue is subsequently sent to a laboratory for histological evaluation, which is reported separately. Post-procedure care includes the application of antibiotic ointment to the biopsy site and, if necessary, an eye patch to protect the area during the initial healing phase.