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Official Description

Radiologic examination, esophagus, including scout chest radiograph(s) and delayed image(s), when performed; double-contrast (eg, high-density barium and effervescent agent) study

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

A radiologic examination of the esophagus, identified by CPT® Code 74221, is a diagnostic imaging procedure that utilizes contrast materials to enhance the visibility of the esophagus during X-ray imaging. This examination employs indirect ionizing radiation to capture images of the esophagus, which is a muscular tube that connects the throat to the stomach. The use of contrast agents, such as high-density barium and an effervescent agent, allows for a clearer distinction of the esophageal structures by highlighting differences in density and composition. The procedure typically begins with one or more scout chest radiographs, which are preliminary X-ray images taken from a front-to-back (anteroposterior) view while the patient is in an erect or semi-reclined position. These initial images help to visualize the surrounding structures of the esophagus before the administration of the contrast material. In a double-contrast study, the patient ingests a barium sulfate mixture that coats the esophagus, along with an effervescent agent that creates gas in the stomach, enhancing the contrast between the barium and the air. This combination allows for a more detailed examination of the esophagus, aiding in the diagnosis of various conditions such as ulcers, tumors, inflammation, scarring, and obstructions. Following the ingestion of the contrast materials, a series of X-ray images are captured to assess the esophagus's condition. Delayed images may also be taken if the movement of the contrast through the esophagus is particularly slow, ensuring that all relevant details are captured for accurate diagnosis. After the imaging is complete, the physician reviews the images, identifies any abnormalities, and provides a comprehensive written interpretation of the findings, which is essential for guiding further clinical management.

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