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Official Description

Radiologic examination, small intestine, including multiple serial images and scout abdominal radiograph(s), when performed; double-contrast (eg, high-density barium and air via enteroclysis tube) study, including glucagon, when administered

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

A radiologic examination of the small intestine, specifically coded as CPT® Code 74251, is a specialized imaging procedure designed to visualize the duodenum, jejunum, and ileum. This examination employs a double-contrast technique, which involves the use of both high-density barium and air, administered via an enteroclysis tube. The process begins with the patient undergoing a series of X-ray images, which utilize indirect ionizing radiation to capture detailed pictures of the internal structures of the body. X-rays are particularly effective in imaging non-uniform materials, such as human tissue, due to the varying densities and compositions of these materials. This differential absorption of X-rays results in a two-dimensional representation of the anatomical structures being examined. The primary purpose of this radiologic examination is to diagnose various conditions affecting the small intestine, including but not limited to ulcers, tumors, inflammation, scarring, obstructions, and any abnormal positioning or configuration of the organs. Patients may present with a range of symptoms that warrant this examination, such as unexplained weight loss, the presence of blood in the stool, abdominal pain, indigestion, or abdominal distention. Before the administration of contrast, the procedure typically begins with one or more anteroposterior (AP) scout films, which are taken with the patient in either an erect or supine position. For a single contrast study, the patient ingests a barium sulfate mixture that coats the gastrointestinal tract. In contrast, the double-contrast study (CPT® Code 74251) involves the infusion of a high-contrast barium sulfate mixture through an enteroclysis tube directly into the duodenum, along with the introduction of air to enhance the imaging quality. Additionally, glucagon may be administered to relax the muscles of the small intestine, facilitating a clearer view of the structures. The radiologist then utilizes fluoroscopic X-ray to visualize the small intestine in real-time, allowing for the observation of its function while obtaining multiple serial images as necessary for a comprehensive assessment.

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