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Official Description

Myocardial imaging, positron emission tomography (PET), combined perfusion with metabolic evaluation study (including ventricular wall motion[s] and/or ejection fraction[s], when performed), dual radiotracer (eg, myocardial viability);

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

A myocardial imaging, positron emission tomography (PET), combined perfusion with metabolic evaluation study (CPT® Code 78432) is a sophisticated non-invasive imaging technique designed to assess the heart muscle's function, blood flow, and overall perfusion. This procedure utilizes radioactive tracers, which are substances that emit radiation, injected into the patient's bloodstream to visualize the heart's activity in real-time. The PET scan generates three-dimensional images that illustrate how blood flows through the heart, providing critical insights into the heart's pumping ability and identifying any potential abnormalities in myocardial viability before any structural changes in the heart tissue occur. The study not only evaluates the perfusion of the heart but also examines metabolic activity within the myocardial cells, which can indicate the presence of disease processes. Key measurements obtained during this study include ventricular wall motion and ejection fraction, both of which are essential indicators of left ventricular function. These metrics are crucial for predicting patient outcomes in the context of existing cardiac conditions. To conduct this study, a dual radiotracer approach is employed, where one tracer measures blood flow (such as rubidium-82 or nitrogen-13) and another assesses metabolic activity (like carbon-11). The procedure is performed in a specialized environment equipped with advanced imaging technology, including a proton (gamma ray) detecting scanner that rotates around the patient. The patient is positioned on a movable table, and intravenous access is established for tracer administration. Electrocardiogram (EKG) leads are attached to monitor the heart's electrical activity, ensuring synchronization with the imaging process. The imaging process involves obtaining a baseline scan followed by the injection of the dual radioactive tracers, with multiple passes through the scanner to capture comprehensive images of the heart from various angles. The distribution of the radioactive tracers within the heart tissue provides valuable information about blood flow, highlighting areas of narrowed coronary vessels, damaged tissue, or scar formation through distinct patterns and colors. When performed concurrently with a CT transmission scan (CPT® Code 78433), this procedure enhances the accuracy of anatomical localization of any damaged tissue or disease processes by integrating PET and CT data, allowing for improved diagnostic precision.

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