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Official Description

Positron emission tomography (PET) with concurrently acquired computed tomography (CT) for attenuation correction and anatomical localization imaging; whole body

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

Positron emission tomography (PET) imaging, commonly known as a PET scan, is a sophisticated diagnostic imaging procedure that provides detailed insights into the physiological processes within the body. This procedure is performed on the whole body and is enhanced by a concurrently acquired computed tomography (CT) scan, which serves two primary purposes: attenuation correction and anatomical localization. During a PET scan, a radioactive substance, referred to as a radioisotope, is administered to the patient, typically through an intravenous line, although inhalation is also a less common method of administration. This radioisotope is produced using a cyclotron, which generates the short-lived isotopes immediately before the procedure. The radioisotope is then tagged to a natural compound, such as glucose, which is preferentially taken up by various tissues and organs in the body. As the radioisotope accumulates in different tissues, it emits positrons, which are detected during the imaging process. The varying rates at which normal and diseased tissues absorb the radioisotope result in distinct colors or brightness levels on the PET images, allowing for the identification of malignant lesions and the assessment of treatment effectiveness for cancers. The patient is required to rest quietly for a period of 30 to 90 minutes post-administration to ensure optimal distribution of the radioisotope before the imaging begins. Concurrently, the CT component of the scan utilizes multiple x-ray beams and electronic detectors to create a series of detailed two-dimensional images, which help to correct for any attenuation that may occur and to accurately localize anatomical structures. The combination of PET and CT imaging provides a comprehensive view of both the functional and structural aspects of the body, enabling healthcare professionals to make informed diagnostic and treatment decisions.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The indications for performing a positron emission tomography (PET) scan with concurrently acquired computed tomography (CT) include the following:

  • Detection of Malignant Lesions PET imaging is primarily utilized for identifying cancerous tumors and assessing their characteristics.
  • Evaluation of Treatment Effectiveness This procedure is used to monitor the response of malignancies to various treatment modalities, such as chemotherapy or radiation therapy.
  • Diagnosis of Other Conditions Beyond oncology, PET imaging can assist in diagnosing and evaluating a range of other medical conditions, including neurological disorders and cardiovascular diseases.

2. Procedure

The procedure for conducting a PET scan with concurrent CT imaging involves several critical steps, which are outlined as follows:

  • Step 1: Patient Preparation The patient is prepared for the PET imaging procedure by placing an intravenous line to facilitate the administration of the radioisotope. It is essential for the patient to remain calm and still during the imaging process to ensure accurate results.
  • Step 2: Administration of Radioisotope A radioisotope, typically tagged to a natural compound like glucose, is administered intravenously. This substance is crucial for the imaging process as it allows for the visualization of metabolic activity within the body.
  • Step 3: Waiting Period After the radioisotope is administered, the patient must rest quietly for a period ranging from 30 to 90 minutes. This waiting period allows the radioisotope to circulate and be absorbed by the tissues and organs that will be imaged.
  • Step 4: Image Acquisition Once the waiting period is complete, PET images are obtained. Concurrently, CT images are captured to provide anatomical context and correct for any attenuation that may affect the clarity of the PET images.
  • Step 5: Image Review After the imaging is completed, a radiologist reviews both the PET and CT images. They analyze the variations in radioisotope accumulation across the body regions studied, comparing the current images with any previous radiological studies to assess changes over time.

3. Post-Procedure

Post-procedure care for patients undergoing a PET scan typically involves monitoring for any immediate reactions to the radioisotope, although serious side effects are rare. Patients may be advised to drink plenty of fluids to help flush the radioisotope from their system. The results of the PET/CT scan will be compiled into a written report by the radiologist, which will detail the findings and any significant variations in radioisotope uptake. This report is then communicated to the referring physician for further evaluation and to guide subsequent treatment decisions.

Short Descr PET IMAGE W/CT FULL BODY
Medium Descr PET IMAGING FOR CT ATTENUATION WHOLE BODY
Long Descr Positron emission tomography (PET) with concurrently acquired computed tomography (CT) for attenuation correction and anatomical localization imaging; whole body
Status Code Carriers Price the Code
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 1 - Diagnostic Tests for Radiology Services
Multiple Procedures (51) 0 - No payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 0 - Payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Procedure or Service, Not Discounted when Multiple
ASC Payment Indicator Radiology service paid separately when provided integral to a surgical procedure on ASC list; payment based on OPPS relative payment weight.
Type of Service (TOS) 4 - Diagnostic Radiology
Berenson-Eggers TOS (BETOS) I2D - Advanced imaging - MRI/MRA: other
MUE 1
CCS Clinical Classification 209 - Radioisotope scan and function studies
26 Professional component: certain procedures are a combination of a physician or other qualified health care professional component and a technical component. when the physician or other qualified health care professional component is reported separately, the service may be identified by adding modifier 26 to the usual procedure number.
PS Positron emission tomography (pet) or pet/computed tomography (ct) to inform the subsequent treatment strategy of cancerous tumors when the beneficiary's treating physician determines that the pet study is needed to inform subsequent anti-tumor strategy
PI Positron emission tomography (pet) or pet/computed tomography (ct) to inform the initial treatment strategy of tumors that are biopsy proven or strongly suspected of being cancerous based on other diagnostic testing
TC Technical component; under certain circumstances, a charge may be made for the technical component alone; under those circumstances the technical component charge is identified by adding modifier 'tc' to the usual procedure number; technical component charges are institutional charges and not billed separately by physicians; however, portable x-ray suppliers only bill for technical component and should utilize modifier tc; the charge data from portable x-ray suppliers will then be used to build customary and prevailing profiles
MG The order for this service does not have applicable appropriate use criteria in the qualified clinical decision support mechanism consulted by the ordering professional
X5 Diagnostic services requested by another clinician: for reporting services by a clinician who furnishes care to the patient only as requested by another clinician or subsequent and related services requested by another clinician; this modifier is reported for patient relationships that may not be adequately captured by the above alternative categories; reporting clinician service examples include but are not limited to, the radiologist's interpretation of an imaging study requested by another clinician
GC This service has been performed in part by a resident under the direction of a teaching physician
ME The order for this service adheres to appropriate use criteria in the clinical decision support mechanism consulted by the ordering professional
KX Requirements specified in the medical policy have been met
MH Unknown if ordering professional consulted a clinical decision support mechanism for this service, related information was not provided to the furnishing professional or provider
GA Waiver of liability statement issued as required by payer policy, individual case
Q6 Service furnished under a fee-for-time compensation arrangement by a substitute physician or by a substitute physical therapist furnishing outpatient physical therapy services in a health professional shortage area, a medically underserved area, or a rural area
77 Repeat procedure by another physician or other qualified health care professional: it may be necessary to indicate that a basic procedure or service was repeated by another physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 77 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
QQ Ordering professional consulted a qualified clinical decision support mechanism for this service and the related data was provided to the furnishing professional
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
MF The order for this service does not adhere to the appropriate use criteria in the clinical decision support mechanism consulted by the ordering professional
GZ Item or service expected to be denied as not reasonable and necessary
MC Ordering professional is not required to consult a clinical decision support mechanism due to the significant hardship exception of electronic health record or clinical decision support mechanism vendor issues
Q0 Investigational clinical service provided in a clinical research study that is in an approved clinical research study
52 Reduced services: under certain circumstances a service or procedure is partially reduced or eliminated at the discretion of the physician or other qualified health care professional. under these circumstances the service provided can be identified by its usual procedure number and the addition of modifier 52, signifying that the service is reduced. this provides a means of reporting reduced services without disturbing the identification of the basic service. note: for hospital outpatient reporting of a previously scheduled procedure/service that is partially reduced or cancelled as a result of extenuating circumstances or those that threaten the well-being of the patient prior to or after administration of anesthesia, see modifiers 73 and 74 (see modifiers approved for asc hospital outpatient use).
53 Discontinued procedure: under certain circumstances, the physician or other qualified health care professional may elect to terminate a surgical or diagnostic procedure. due to extenuating circumstances or those that threaten the well being of the patient, it may be necessary to indicate that a surgical or diagnostic procedure was started but discontinued. this circumstance may be reported by adding modifier 53 to the code reported by the individual for the discontinued procedure. note: this modifier is not used to report the elective cancellation of a procedure prior to the patient's anesthesia induction and/or surgical preparation in the operating suite. for outpatient hospital/ambulatory surgery center (asc) reporting of a previously scheduled procedure/service that is partially reduced or cancelled as a result of extenuating circumstances or those that threaten the well being of the patient prior to or after administration of anesthesia, see modifiers 73 and 74 (see modifiers approved for asc hospital outpatient use).
76 Repeat procedure or service by same physician or other qualified health care professional: it may be necessary to indicate that a procedure or service was repeated by the same physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 76 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
99 Multiple modifiers: under certain circumstances 2 or more modifiers may be necessary to completely delineate a service. in such situations modifier 99 should be added to the basic procedure, and other applicable modifiers may be listed as part of the description of the service.
AQ Physician providing a service in an unlisted health professional shortage area (hpsa)
CC Procedure code change (use 'cc' when the procedure code submitted was changed either for administrative reasons or because an incorrect code was filed)
CR Catastrophe/disaster related
GV Attending physician not employed or paid under arrangement by the patient's hospice provider
GW Service not related to the hospice patient's terminal condition
JZ Zero drug amount discarded/not administered to any patient
LT Left side (used to identify procedures performed on the left side of the body)
MA Ordering professional is not required to consult a clinical decision support mechanism due to service being rendered to a patient with a suspected or confirmed emergency medical condition
MB Ordering professional is not required to consult a clinical decision support mechanism due to the significant hardship exception of insufficient internet access
MD Ordering professional is not required to consult a clinical decision support mechanism due to the significant hardship exception of extreme and uncontrollable circumstances
MS Six month maintenance and servicing fee for reasonable and necessary parts and labor which are not covered under any manufacturer or supplier warranty
PA Surgical or other invasive procedure on wrong body part
PT Colorectal cancer screening test; converted to diagnostic test or other procedure
Q1 Routine clinical service provided in a clinical research study that is in an approved clinical research study
QJ Services/items provided to a prisoner or patient in state or local custody, however the state or local government, as applicable, meets the requirements in 42 cfr 411.4 (b)
RT Right side (used to identify procedures performed on the right side of the body)
TP Medical transport, unloaded vehicle
XE Separate encounter, a service that is distinct because it occurred during a separate encounter
XP Separate practitioner, a service that is distinct because it was performed by a different practitioner
XS Separate structure, a service that is distinct because it was performed on a separate organ/structure
XU Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service
Date
Action
Notes
2011-01-01 Changed Short description changed.
2008-01-01 Changed Code description changed.
2005-01-01 Added First appearance in code book in 2005.
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