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Official Description

Radiopharmaceutical localization of tumor, inflammatory process or distribution of radiopharmaceutical agent(s) (includes vascular flow and blood pool imaging, when performed); tomographic (SPECT) with concurrently acquired computed tomography (CT) transmission scan for anatomical review, localization and determination/detection of pathology, single area (eg, head, neck, chest, pelvis) or acquisition, single day imaging

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 78830 refers to a specialized imaging procedure known as radiopharmaceutical localization, which is utilized for identifying tumors or inflammatory processes within the body. This procedure employs molecular imaging techniques, specifically single photon emission computed tomography (SPECT), in conjunction with a computed tomography (CT) scan that is acquired simultaneously. The use of a radiolabeled isotope tracer is central to this process, as it allows for the precise localization of pathological conditions, including tumors and areas of inflammation. The radiopharmaceutical agent is designed to bind to specific tissues, enabling the detection of abnormalities even in their early stages. During the procedure, an intravenous line is established to facilitate the injection of the radiolabeled isotope tracer directly into the patient's circulatory system. Alternatively, a blood sample may be taken, processed to isolate certain blood cells, and then tagged with the isotope before being reintroduced into the patient. In some cases, radioactive agents may also be administered through inhalation or ingestion. Once the tracer is in the body, it circulates and accumulates in areas of interest, such as inflamed or tumorous tissues. The imaging process involves positioning the patient on a specialized imaging table, where a gamma camera, capable of performing both SPECT and CT scans, is aligned over the targeted area. The scanning occurs at predetermined intervals, capturing the radioactive energy emitted from the tracer, which is then converted into detailed images. This hybrid imaging technique not only provides a three-dimensional view of the area under investigation but also allows for anatomical review and localization of any detected pathology. The entire procedure is typically completed in a single day, focusing on one specific area of the body, such as the head, neck, chest, or pelvis. Following the imaging, the physician interprets the results and generates a comprehensive written report detailing the findings.

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