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Radiopharmaceutical therapy by oral administration involves the ingestion of a specific dose of a radioisotope, which can be delivered in various forms such as a liquid, tablet, or capsule. This therapeutic approach is designed to treat specific diseases or conditions by utilizing the properties of the radioisotope. Once ingested, the radioisotope travels through the body's normal physiological pathways, ultimately reaching the targeted organ or tissue where it exerts its therapeutic effects. A notable example of this type of therapy is the use of Iodine-131, which is commonly administered to patients for the treatment of hyperthyroidism and certain types of thyroid gland cancers. The mechanism of action relies on the radioisotope's ability to selectively accumulate in the thyroid tissue, allowing for localized treatment while minimizing exposure to surrounding healthy tissues.
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