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Official Description

Urinalysis; qualitative or semiquantitative, except immunoassays

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 81005 refers to a urinalysis that is qualitative or semiquantitative in nature, excluding immunoassays. This laboratory test is essential for detecting abnormal cellular material or substances present in urine. The qualitative or semiquantitative urinalysis serves as a routine screening tool, allowing healthcare professionals to identify various substances such as protein, glucose, bacteria, and red or white blood cells that may indicate underlying health issues requiring further investigation. Additionally, this test can be utilized to monitor organ function and assess the response to treatment in patients who have pre-existing conditions. The urinalysis process typically involves a visual examination, chemical analysis, and may also include a microscopic study of the urine sample. To collect the urine sample, methods such as clean catch, mid-stream void, or catheterization are employed. The initial visual assessment focuses on the urine's color, odor, and clarity. Following this, the urine is applied to a plastic test strip that contains several reagent areas, each impregnated with specific chemicals. The resulting color changes in these reagent areas are then compared to a standardized chart to evaluate parameters such as pH level, specific gravity, and the presence or absence of substances like glucose, bilirubin, ketones, blood, protein, urobilinogen, nitrate, leukocytes, and ascorbic acid. In some cases, the urine sample may be centrifuged to separate the fluid from the sediment, which is then examined microscopically for the presence of crystals, casts, squamous cells, red or white blood cells, epithelial cells, bacteria, or yeast cells. The findings from this examination are meticulously counted and reported, providing valuable insights into the patient's health status.

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