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Official Description

Acetaminophen

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 82003 refers to a laboratory test specifically designed to measure the levels of acetaminophen in the blood. Acetaminophen, commonly known by the brand name Tylenol, is classified as an analgesic and antipyretic medication, which means it is used to alleviate mild to moderate pain and reduce fever. This medication can be administered in various forms, including orally in tablet or liquid form, or via rectal suppository. While acetaminophen is generally safe when used as directed, excessive intake can lead to serious health complications, including toxic hepatitis, a condition that can cause liver damage. Therefore, monitoring blood levels of acetaminophen becomes critical in cases of suspected overdose or when patients exhibit signs and symptoms of toxicity. The testing process involves obtaining a blood sample through a procedure known as venipuncture, which is reported separately. Following the collection of the blood sample, the serum is analyzed using a method called spectrophotometry, which allows for accurate measurement of acetaminophen concentration in the bloodstream. Regular monitoring of acetaminophen levels is typically conducted every 4 to 6 hours, with particular attention given to critical values that are noted at 4 and 12 hours post-ingestion to ensure patient safety and appropriate medical intervention.

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