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Official Description

Ketone body(s) (eg, acetone, acetoacetic acid, beta-hydroxybutyrate); quantitative

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 82010 refers to a quantitative test for ketone bodies in the blood, specifically measuring substances such as acetone, acetoacetic acid, and beta-hydroxybutyrate. This test is crucial for assessing the levels of ketone bodies, which are produced when the body breaks down fat for energy instead of carbohydrates. The presence of these ketone bodies can indicate various metabolic states, particularly in conditions where carbohydrate utilization is impaired. For instance, elevated levels of ketone bodies are commonly associated with diabetes mellitus, where the body cannot effectively use glucose due to insulin deficiency or resistance. Additionally, this test can be relevant in cases of malnutrition, anorexia, inadequate calorie intake, vomiting, and glycogen storage diseases. The quantitative aspect of this test distinguishes it from the qualitative test (CPT® Code 82009), which only determines the presence or absence of ketone bodies through a visual assessment. The qualitative test is often described as semi-quantitative due to its reliance on color changes to indicate low to high levels of ketones. In contrast, the quantitative test provides a precise measurement of ketone levels in the blood serum, which is essential for the evaluation and management of conditions such as diabetic and alcoholic ketoacidosis. This test is typically performed on a blood sample obtained through venipuncture, and the analysis is conducted using gas chromatography, a method that allows for accurate quantification of the ketone bodies present in the serum.

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