CPT® Code 82380

The CPT® Code 82380 refers to the laboratory test for measuring carotene levels in the blood. Carotene is a type of polyunsaturated hydrocarbon predominantly found in various plants, existing mainly in two isomeric forms: beta-carotene and alpha-carotene. These compounds are recognized for their antioxidant properties and are vital nutrients for human health. The measurement of carotene levels is significant as decreased levels can indicate potential health issues, such as inadequate dietary fat intake, the presence of intestinal parasites, certain fat malabsorption syndromes, and diseases affecting the kidney, liver, or pancreas. Additionally, certain medications can interfere with the absorption of carotenes, including cholestyramine, alcohol, fat-binding weight loss drugs, and fiber supplements. Conversely, elevated carotene levels may be associated with conditions such as hypothyroidism, diabetes, myxedema, chronic nephritis, and excessive intake of vitamin supplements. The test involves obtaining a blood sample through venipuncture, which is reported separately. The analysis of the blood serum is conducted to determine total carotene levels using quantitative spectrophotometry, while fractionated carotene levels (including alpha, beta, lutein, and zeaxanthin) can be assessed using qualitative high-performance liquid chromatography.