CPT® Code 82384

The CPT® Code 82384 refers to the measurement of fractionated catecholamines, which are critical hormones produced by the adrenal glands and nerve tissues, including the brain. This test is essential for assessing the levels of three specific catecholamines: dopamine, norepinephrine, and epinephrine (commonly known as adrenaline). Elevated levels of these hormones can indicate the presence of neuroendocrine tumors, such as pheochromocytoma or neuroblastoma, which are conditions that may require further medical evaluation and intervention. The test can be performed using either a blood sample or a urine sample collected over a 24-hour period. For the blood test, it is recommended that the patient be calm and in a supine position for at least 30 minutes prior to the venipuncture to ensure accurate results. The analysis of the blood sample is conducted using quantitative high-performance liquid chromatography, while the urine sample is analyzed using quantitative tandem mass spectrometry. This fractionated approach allows for a detailed understanding of each hormone's levels, providing valuable information for diagnosis and treatment planning.