CPT® Code 82435

The CPT® Code 82435 refers to the laboratory test for measuring chloride levels in a blood sample. Chloride is a crucial negatively charged electrolyte that plays a significant role in various physiological processes within the body. It works in conjunction with other electrolytes, including potassium, sodium, and carbon dioxide (CO2), to help regulate fluid balance and maintain the proper acid-base equilibrium. Chloride is present in all body fluids, with the highest concentration found in the blood. The levels of chloride typically mirror those of sodium, meaning that when sodium levels rise or fall, chloride levels tend to follow suit, except in cases of acid-base imbalances. In such instances, chloride functions as a buffer, allowing its levels to fluctuate independently of sodium. The measurement of chloride is essential for screening and monitoring electrolyte levels and acid-base balance, and it is typically performed using ion-selective electrode (ISE) methodology, which provides accurate and reliable results for clinical assessment.