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Official Description

Chromium

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 82495 refers to the laboratory test for measuring chromium levels in blood or urine. Chromium is an essential trace mineral that exists in two primary forms: trivalent and hexavalent. The trivalent form is biologically active and plays a crucial role in maintaining optimal health, particularly in glucose metabolism and insulin function. In contrast, hexavalent chromium is a toxic compound often associated with industrial pollution and can pose significant health risks upon exposure. The measurement of chromium levels through laboratory testing is important for assessing an individual's nutritional status and for screening potential exposure to toxic waste. It is essential to note that various factors, including nutritional supplements, medications, and iodine-containing contrast media, can influence the accuracy of test results. The collection of samples for this test can be performed through venipuncture for blood samples, which must be reported separately, or through urine collection, which may be done over a 24-hour period or as a single random sample. Both serum and urine samples are analyzed using quantitative inductively coupled plasma-mass spectrometry, a highly sensitive technique that allows for precise measurement of chromium concentrations.

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