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Official Description

Cortisol; total

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

Cortisol is a glucocorticoid, which is a type of steroid hormone produced by the adrenal glands in response to stress. This hormone plays a crucial role in various bodily functions, including the regulation of blood glucose levels, suppression of the immune system, and the metabolism of fats, proteins, and carbohydrates. The measurement of cortisol levels is significant in diagnosing certain medical conditions. For instance, elevated cortisol levels may indicate Cushing syndrome, a disorder characterized by excessive cortisol production, while decreased levels may suggest Addison disease, a condition where the adrenal glands do not produce sufficient hormones. The CPT® Code 82533 specifically refers to the testing of total cortisol levels in blood or saliva samples. This test is essential for assessing adrenal function and can provide valuable insights into a patient's health status. The collection of samples for this test is performed through separate reportable procedures, ensuring that the results are accurate and reliable for clinical evaluation.

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