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Column chromatography/mass spectrometry is a sophisticated analytical technique that combines the principles of chromatography and mass spectrometry to analyze chemical substances. In this method, chromatography is employed to separate various chemical components within a sample during two distinct phases: the stationary phase and the mobile phase, which can be either gas or liquid. Once the components are separated, they are directed into a mass spectrometer, which captures and measures the isolated molecules as they elute from the chromatography column. This process is crucial for determining the precise chemical structure of the components being analyzed. The technique is particularly noted for its high sensitivity and selectivity, making it effective for analyzing complex mixtures that may contain multiple elements or intermediates. Common applications of this method include the detection of compounds in biological samples, such as blood or other bodily fluids, where it is used to identify chemical contaminants. It is important to note that the qualitative nature of this test means it is designed to confirm the presence of an analyte without quantifying the exact concentration of the substance in the sample.
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Column chromatography/mass spectrometry is indicated for the analysis of various chemical components in samples where the identification of specific non-drug analytes is required. This procedure is particularly useful in the following scenarios:
The procedure for column chromatography/mass spectrometry involves several key steps that ensure accurate separation and identification of chemical components. Each step is critical to the overall success of the analysis.
After the completion of the column chromatography/mass spectrometry procedure, it is essential to ensure proper handling and analysis of the results. The data generated must be carefully reviewed to confirm the presence of the analytes of interest. Additionally, any remaining samples should be stored appropriately for potential further analysis. It is also important to document the findings accurately, as this information may be critical for clinical or research purposes. Follow-up actions may include further testing or analysis based on the results obtained from this qualitative assessment.
| Short Descr | COLUMN CHROMOTOGRAPHY QUAL | Medium Descr | COL-CHR/MS QUAL 1 STATIONARY&MOBILE PHASE NES | Long Descr | Column chromatography/mass spectrometry (eg, GC/MS, or HPLC/MS), non-drug analyte not elsewhere specified; qualitative, single stationary and mobile phase | Status Code | Statutory Exclusion (from MPFS, may be paid under other methodologies) | Global Days | XXX - Global Concept Does Not Apply | PC/TC Indicator (26, TC) | 9 - Not Applicable | Multiple Procedures (51) | 9 - Concept does not apply. | Bilateral Surgery (50) | 9 - Concept does not apply. | Physician Supervisions | 09 - Concept does not apply. | Assistant Surgeon (80, 82) | 9 - Concept does not apply. | Co-Surgeons (62) | 9 - Concept does not apply. | Team Surgery (66) | 9 - Concept does not apply. | Diagnostic Imaging Family | 99 - Concept Does Not Apply | APC Status Indicator | Items and Services Packaged into APC Rates | Type of Service (TOS) | 5 - Diagnostic Laboratory | Berenson-Eggers TOS (BETOS) | T1H - Lab tests - other (non-Medicare fee schedule) | MUE | Not applicable/unspecified. | CCS Clinical Classification | 233 - Laboratory - Chemistry and Hematology |
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| 2016-01-01 | Deleted | Code deleted, to report see specific analyte or 82542 |
| 2015-01-01 | Changed | Description Changed |
| 2011-01-01 | Changed | Short description changed. |
| 2001-01-01 | Changed | Code description changed. |
| 1999-01-01 | Added | First appearance in code book in 1999. |
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