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Official Description

Vitamin D; 1, 25 dihydroxy, includes fraction(s), if performed

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 82652 refers to the laboratory test for measuring blood levels of 1, 25-dihydroxyvitamin D, which is a biologically active form of vitamin D. This test is particularly significant in clinical settings where there is a suspicion of elevated calcium levels in the blood, as it aids in diagnosing conditions that may lead to abnormal vitamin D metabolism and calcium regulation. Such conditions include diseases like sarcoidosis and lymphoma, which can cause the body to produce excess vitamin D. Additionally, the measurement of 1, 25-dihydroxyvitamin D is crucial for evaluating the function of the parathyroid glands, which play a vital role in calcium homeostasis. The procedure involves obtaining a blood sample from the patient, and the analysis is typically performed using a method known as radioimmunoassay. The results of this test may provide a comprehensive view of the patient's vitamin D status, reflecting both the total levels of 1, 25-dihydroxyvitamin D and any fractions that may be present, thereby offering valuable insights for diagnosis and monitoring of related health issues.

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