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Official Description

Gammaglobulin (immunoglobulin); IgA, IgD, IgG, IgM, each

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 82784 refers to the laboratory test for measuring the levels of immunoglobulins, specifically IgA, IgD, IgG, and IgM, in blood or other body fluids such as saliva or cerebrospinal fluid (CSF). Immunoglobulins, commonly known as antibodies, play a crucial role in the immune system by identifying and neutralizing pathogens like bacteria and viruses. This test is essential for diagnosing a range of medical conditions, including autoimmune diseases, allergies, and certain types of cancers such as multiple myeloma and macroglobulinemia. Additionally, it is utilized to assess patients who experience frequent infections, as low levels of immunoglobulin IgG may indicate an underlying immunodeficiency. The evaluation of immunoglobulin levels can also provide insights into the effectiveness of treatments for conditions like cancer or infections caused by Helicobacter pylori. There are five primary types of immunoglobulins: IgA, IgD, IgE, IgG, and IgM, each serving distinct functions in the immune response. For instance, IgA is predominantly found in mucosal areas, providing a first line of defense against pathogens, while IgG is the most abundant antibody in circulation, crucial for combating bacterial and viral infections. The methodology for testing these immunoglobulins varies based on the specimen type and the specific immunoglobulin being analyzed. To report each immunoglobulin determination, the appropriate CPT® codes must be utilized, ensuring accurate documentation and billing for the laboratory services rendered.

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