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Official Description

Gases, blood, any combination of pH, pCO2, pO2, CO2, HCO3 (including calculated O2 saturation); with O2 saturation, by direct measurement, except pulse oximetry

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 82805 refers to a laboratory test that measures various components of blood gases, specifically assessing the homeostatic acid-base balance in the body. This test evaluates blood pH, which indicates the concentration of hydrogen ions (H+) in the blood, providing insight into the acidity or alkalinity of the blood. Additionally, it measures the partial pressure of carbon dioxide (pCO2), which reflects the efficiency of the lungs in expelling carbon dioxide from the body. The partial pressure of oxygen (pO2) is also measured, indicating the level of oxygen dissolved in the blood and the effectiveness of oxygen exchange in the alveoli of the lungs. Furthermore, bicarbonate (HCO3) is included in this test, which is calculated based on the pH and pCO2 values, representing the metabolic aspect of acid-base balance and the kidneys' response to changes in blood pH. Oxygen saturation (O2 Sat) is another critical component measured directly, providing a precise percentage of hemoglobin that is saturated with oxygen, which is particularly important in critically ill patients who may be at risk for tissue hypoxia. The direct measurement of O2 Sat is performed using a blood gas analyzer equipped with CO-oximetry, ensuring accuracy in the results. Blood gas monitoring is essential for evaluating lung function, detecting acid-base imbalances, monitoring various disorders related to metabolism, respiration, and kidney function, as well as assessing the effectiveness of ongoing treatments. To perform this test, a blood sample is obtained through methods such as venipuncture, heel stick, arterial draw, or umbilical cord draw, which are separately reportable procedures.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The CPT® Code 82805 is indicated for use in various clinical scenarios where assessment of blood gases is necessary. The following conditions and symptoms may warrant this laboratory test:

  • Evaluation of Lung Function This test is performed to assess how well the lungs are functioning, particularly in patients with respiratory conditions.
  • Detection of Acid-Base Imbalance It helps in identifying any disturbances in the acid-base balance of the body, which can be critical in managing various health conditions.
  • Monitoring of Metabolic Disorders The test is useful in tracking metabolic disorders that may affect acid-base balance and overall health.
  • Assessment of Respiratory Disorders It is indicated for patients with respiratory disorders to monitor their condition and response to treatment.
  • Evaluation of Kidney Disorders The test can assist in evaluating kidney function and its role in maintaining acid-base balance.
  • Effectiveness of Treatment It is used to assess the effectiveness of therapeutic interventions in patients with respiratory or metabolic issues.

2. Procedure

The procedure for obtaining the necessary blood gas measurements involves several key steps, which are outlined below:

  • Step 1: Patient Preparation Prior to the procedure, the patient may need to be prepared based on the specific clinical scenario. This may include ensuring that the patient is in a stable condition and has not recently undergone any activities that could affect the results, such as smoking or vigorous exercise.
  • Step 2: Blood Sample Collection A blood sample is obtained using one of several methods, including venipuncture, heel stick (for infants), arterial draw, or umbilical cord draw (for newborns). The choice of method depends on the patient's age, condition, and the clinical setting.
  • Step 3: Sample Handling Once the blood sample is collected, it must be handled carefully to prevent contamination and ensure accurate results. The sample should be placed in a heparinized syringe or appropriate container to preserve the gas levels.
  • Step 4: Analysis The blood sample is then analyzed using a blood gas analyzer, which measures the pH, pCO2, pO2, HCO3, and O2 saturation. The analyzer provides direct measurements, particularly for O2 saturation, which is crucial for accurate assessment.
  • Step 5: Interpretation of Results After analysis, the results are interpreted by healthcare professionals to evaluate the patient's respiratory and metabolic status, guiding further clinical decisions and management.

3. Post-Procedure

After the blood gas analysis procedure, the patient may require monitoring based on their clinical condition. It is essential to observe for any complications related to the blood draw, such as bleeding or infection at the puncture site. The healthcare provider will review the results of the blood gas analysis to determine if any immediate interventions are necessary. Depending on the findings, further diagnostic tests or treatments may be initiated to address any identified issues, such as respiratory distress or metabolic imbalances. Patients may also receive instructions on follow-up care or additional testing if required.

Short Descr BLOOD GASES W/O2 SATURATION
Medium Descr GASES BLOOD PH DIRECT MEAS XCPT PULSE OXIMITRY
Long Descr Gases, blood, any combination of pH, pCO2, pO2, CO2, HCO3 (including calculated O2 saturation); with O2 saturation, by direct measurement, except pulse oximetry
Status Code Statutory Exclusion (from MPFS, may be paid under other methodologies)
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 9 - Not Applicable
Multiple Procedures (51) 9 - Concept does not apply.
Bilateral Surgery (50) 9 - Concept does not apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 9 - Concept does not apply.
Co-Surgeons (62) 9 - Concept does not apply.
Team Surgery (66) 9 - Concept does not apply.
Diagnostic Imaging Family 99 - Concept Does Not Apply
CLIA Waived (QW) No
APC Status Indicator Conditionally packaged laboratory tests
Type of Service (TOS) 5 - Diagnostic Laboratory
Berenson-Eggers TOS (BETOS) T1H - Lab tests - other (non-Medicare fee schedule)
MUE 2
CCS Clinical Classification 205 - Arterial blood gases
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
90 Reference (outside) laboratory: when laboratory procedures are performed by a party other than the treating or reporting physician or other qualified health care professional, the procedure may be identified by adding modifier 90 to the usual procedure number.
26 Professional component: certain procedures are a combination of a physician or other qualified health care professional component and a technical component. when the physician or other qualified health care professional component is reported separately, the service may be identified by adding modifier 26 to the usual procedure number.
91 Repeat clinical diagnostic laboratory test: in the course of treatment of the patient, it may be necessary to repeat the same laboratory test on the same day to obtain subsequent (multiple) test results. under these circumstances, the laboratory test performed can be identified by its usual procedure number and the addition of modifier 91. note: this modifier may not be used when tests are rerun to confirm initial results; due to testing problems with specimens or equipment; or for any other reason when a normal, one-time, reportable result is all that is required. this modifier may not be used when other code(s) describe a series of test results (eg, glucose tolerance tests, evocative/suppression testing). this modifier may only be used for laboratory test(s) performed more than once on the same day on the same patient.
GA Waiver of liability statement issued as required by payer policy, individual case
GV Attending physician not employed or paid under arrangement by the patient's hospice provider
GW Service not related to the hospice patient's terminal condition
GZ Item or service expected to be denied as not reasonable and necessary
Q1 Routine clinical service provided in a clinical research study that is in an approved clinical research study
Date
Action
Notes
2011-01-01 Changed Short description changed.
1994-01-01 Added First appearance in code book in 1994.
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