CPT® Code 82975

Deleted

A laboratory test is conducted to assess the concentration of glutamine, also known as glutamic acid amide, which is classified as a non-essential amino acid. Glutamine is a vital component found in high concentrations throughout the body, particularly stored in muscle tissue and present in the bloodstream. The synthesis of glutamine occurs through a biochemical reaction involving glutamate and ammonia, facilitated by the enzyme known as glutamine synthetase. This amino acid plays a crucial role in maintaining the acid-base equilibrium within the kidneys by generating ammonium ions. In situations where glucose is scarce, glutamine serves as an alternative energy source for cells. Additionally, it contributes nitrogen during anabolic processes, such as purine synthesis, and provides carbon for the citric acid cycle, which is essential for cellular respiration. Glutamine is also recognized for its function as a non-toxic transporter of ammonia within the bloodstream. This amino acid is actively utilized by various cells, including those in the intestines and kidneys, as well as by lymphocytes and macrophages, which are integral to the immune response. Furthermore, glutamine is important for the proper functioning of the brain, muscles, and endocrine system. To evaluate glutamine levels, samples from serum, urine, and spinal fluid can be analyzed using advanced techniques such as liquid chromatography-tandem mass spectrometry.