CPT® Code 82985

The CPT® Code 82985 refers to a laboratory test that measures glycated protein levels in the blood. Glycated proteins are formed when glucose molecules bind to proteins, and this test is not limited to a specific type of glycated protein. It can be utilized to evaluate various glycated proteins, including glycated albumin, fructosamine, and alpha 1 acid glycoprotein (A1AG). The measurement of glycated albumin or fructosamine is particularly relevant for diabetic patients, as it helps in monitoring blood glucose levels over a period of 2 to 3 weeks. This timeframe is crucial for assessing the effectiveness of any changes made to the patient's treatment plan. An increase in glycated albumin or fructosamine levels indicates that the average blood glucose levels have been elevated during this period. Additionally, the test can be used to evaluate A1AG levels, which is an acute-phase protein produced by the liver. Elevated levels of A1AG are associated with inflammation and an increased risk of cardiovascular disease. The test requires a blood sample, which is obtained through a separately reportable venipuncture. The methodologies for testing include quantitative boronate affinity chromatography/immunoturbidimetric for glycated albumin, quantitative spectrophotometry for fructosamine, and quantitative nephelometry for A1AG. It is important to note that ascorbic acid (Vitamin C) can affect the results of fructosamine testing, and patients should refrain from consuming it 24 hours prior to the blood draw.