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Official Description

Helicobacter pylori; drug administration

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 83014 refers to the administration of a drug specifically for the purpose of conducting a test to detect Helicobacter pylori (H. pylori) infection. H. pylori is a type of bacterium that resides in the stomach and is known to cause various gastrointestinal conditions, including chronic active gastritis, duodenal ulcers, and nonulcerative dyspepsia. The test involves measuring the urease activity in exhaled breath, which is indicative of the presence of H. pylori. The procedure begins with the collection of a baseline breath sample from the patient, followed by the oral administration of a solution or capsule containing 75 mg of (13) C-urea, known as Pranactin-Citric. This compound is metabolized in the stomach by H. pylori, leading to the production of (13) CO2, which is then absorbed into the bloodstream and subsequently exhaled. A second breath sample is collected approximately 13 to 18 minutes after ingestion to assess the presence of H. pylori through quantitative infrared spectrophotometry. It is important to note that while code 83014 pertains to the administration of the medication and the collection of breath samples, code 83013 is utilized for the analysis of the breath sample itself, which includes the necessary medication and test supplies.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The procedure associated with CPT® Code 83014 is indicated for the diagnosis and monitoring of Helicobacter pylori infection in patients presenting with specific gastrointestinal conditions. These indications include:

  • Chronic Active Gastritis - A condition characterized by inflammation of the stomach lining that persists over time, often associated with H. pylori infection.
  • Duodenal Ulcer - An ulcer that occurs in the first part of the small intestine (duodenum), which can be caused by H. pylori infection.
  • Nonulcerative Dyspepsia - A term used to describe symptoms of indigestion that are not associated with ulcers, which may also be linked to H. pylori presence.

2. Procedure

The procedure for CPT® Code 83014 involves several critical steps to ensure accurate testing for H. pylori infection. The steps are as follows:

  • Step 1: Baseline Breath Sample Collection - Initially, a baseline breath sample is collected from the patient. This sample serves as a control to compare against the subsequent sample after the administration of the test substance.
  • Step 2: Administration of Pranactin-Citric - Following the collection of the baseline sample, the patient is instructed to orally ingest a capsule or solution containing 75 mg of (13) C-urea, known as Pranactin-Citric. This compound is crucial for the detection of H. pylori, as it is metabolized by the bacterium.
  • Step 3: Second Breath Sample Collection - After a waiting period of approximately 13 to 18 minutes post-ingestion, a second breath sample is collected. This sample is analyzed to determine the presence of (13) CO2, which indicates the activity of H. pylori in the stomach.
  • Step 4: Analysis of Exhaled Breath - The collected breath samples are then subjected to quantitative infrared spectrophotometry. This analytical technique measures the concentration of (13) CO2 in the exhaled breath, providing evidence of H. pylori infection based on the urease activity.

3. Post-Procedure

After the completion of the procedure associated with CPT® Code 83014, patients may be monitored for any immediate reactions to the ingestion of Pranactin-Citric. Typically, there are no significant post-procedure care requirements, and patients can resume normal activities shortly after the test. However, it is essential for healthcare providers to ensure that patients understand the importance of follow-up consultations to discuss the results of the breath test and any necessary further actions based on the findings.

Short Descr H PYLORI DRUG ADMIN
Medium Descr HPYLORI DRUG ADMINISTRATION
Long Descr Helicobacter pylori; drug administration
Status Code Statutory Exclusion (from MPFS, may be paid under other methodologies)
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 9 - Not Applicable
Multiple Procedures (51) 9 - Concept does not apply.
Bilateral Surgery (50) 9 - Concept does not apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 9 - Concept does not apply.
Co-Surgeons (62) 9 - Concept does not apply.
Team Surgery (66) 9 - Concept does not apply.
Diagnostic Imaging Family 99 - Concept Does Not Apply
CLIA Waived (QW) No
APC Status Indicator Conditionally packaged laboratory tests
Type of Service (TOS) 5 - Diagnostic Laboratory
Berenson-Eggers TOS (BETOS) T1H - Lab tests - other (non-Medicare fee schedule)
MUE 1
CCS Clinical Classification 233 - Laboratory - Chemistry and Hematology
90 Reference (outside) laboratory: when laboratory procedures are performed by a party other than the treating or reporting physician or other qualified health care professional, the procedure may be identified by adding modifier 90 to the usual procedure number.
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
GA Waiver of liability statement issued as required by payer policy, individual case
Q4 Service for ordering/referring physician qualifies as a service exemption
77 Repeat procedure by another physician or other qualified health care professional: it may be necessary to indicate that a basic procedure or service was repeated by another physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 77 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
26 Professional component: certain procedures are a combination of a physician or other qualified health care professional component and a technical component. when the physician or other qualified health care professional component is reported separately, the service may be identified by adding modifier 26 to the usual procedure number.
76 Repeat procedure or service by same physician or other qualified health care professional: it may be necessary to indicate that a procedure or service was repeated by the same physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 76 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
91 Repeat clinical diagnostic laboratory test: in the course of treatment of the patient, it may be necessary to repeat the same laboratory test on the same day to obtain subsequent (multiple) test results. under these circumstances, the laboratory test performed can be identified by its usual procedure number and the addition of modifier 91. note: this modifier may not be used when tests are rerun to confirm initial results; due to testing problems with specimens or equipment; or for any other reason when a normal, one-time, reportable result is all that is required. this modifier may not be used when other code(s) describe a series of test results (eg, glucose tolerance tests, evocative/suppression testing). this modifier may only be used for laboratory test(s) performed more than once on the same day on the same patient.
AY Item or service furnished to an esrd patient that is not for the treatment of esrd
GC This service has been performed in part by a resident under the direction of a teaching physician
GW Service not related to the hospice patient's terminal condition
GY Item or service statutorily excluded, does not meet the definition of any medicare benefit or, for non-medicare insurers, is not a contract benefit
GZ Item or service expected to be denied as not reasonable and necessary
Date
Action
Notes
2005-01-01 Changed Code description changed.
2001-01-01 Changed Code description changed.
1999-01-01 Added First appearance in code book in 1999.
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