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Official Description

Immunoassay for analyte other than infectious agent antibody or infectious agent antigen; quantitative, by radioimmunoassay (eg, RIA)

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 83519 refers to a specific type of immunoassay that is utilized for the quantitative measurement of an analyte, which is a chemical substance other than an infectious agent antibody or antigen. This procedure is particularly significant in the realm of laboratory diagnostics, as it allows for the detection and quantification of various substances that may be indicative of non-infectious diseases and disorders. The term 'quantitative' indicates that the test provides a precise measurement of the analyte's concentration in the sample, rather than merely indicating its presence or absence. The radioimmunoassay (RIA) method, which is the focus of this code, employs radioisotope-labeled antigens or other substances that bind to the specific analyte being tested. This binding process enables the accurate quantification of minute quantities of various substances, including enzymes and hormones, which are critical for diagnosing conditions such as myasthenia gravis, pancreatic disease, and parathyroid disease, among others. In practice, the use of CPT® Code 83519 is essential for reporting quantitative RIA tests, which are distinguished from other quantitative testing methods, such as those reported under CPT® Code 83520. The RIA technique is particularly valuable in clinical settings where precise measurements of specific analytes are necessary for effective patient management and treatment planning.

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