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Official Description

Insulin; total

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

Insulin is a crucial hormone produced by the pancreas that plays a vital role in the regulation of blood glucose levels. It facilitates the utilization of circulating glucose for energy, while also promoting the storage of excess glucose as glycogen in liver and muscle cells. The measurement of total insulin levels in the blood is essential for assessing various metabolic conditions, particularly those related to diabetes and insulin resistance. The procedure involves obtaining a blood sample through a process known as venipuncture, which is separately reportable. The specimen can be collected at a random time, or it may be taken when the patient is fasting, or at specific timed intervals (30, 60, 90, or 120 minutes) following a 75-gram glucose challenge. The test for total insulin levels, identified by CPT® Code 83525, utilizes a quantitative chemiluminescent immunoassay to analyze serum or plasma samples. This method provides a precise measurement of the total insulin present in the bloodstream, which is critical for diagnosing and managing conditions related to insulin production and glucose metabolism.

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