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Official Description

Lactate (lactic acid)

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 83605 refers to the laboratory test for measuring lactate, also known as lactic acid, levels in blood or other body fluids. Lactic acid is a byproduct of anaerobic metabolism, primarily produced by muscle tissues and red blood cells during periods of low oxygen availability. This test is crucial for assessing metabolic conditions, as elevated lactate levels can indicate various physiological stresses on the body. Conditions that may lead to increased lactate production include strenuous physical exercise, heart failure, severe infections such as sepsis, and different shock states, including cardiogenic and hypovolemic shock. Additionally, liver disease can also contribute to elevated lactate levels. The test typically requires a blood sample, which is obtained through a procedure known as venipuncture. In some cases, cerebrospinal fluid (CSF) may be collected via lumbar puncture, commonly referred to as a spinal tap, to measure lactate levels in that fluid. Other body fluids may also be collected for testing. The analysis of plasma, CSF, and other body fluids is performed using enzymatic methodology, which provides accurate measurements of lactate concentrations.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

Testing for lactate (lactic acid) levels is indicated in various clinical scenarios where metabolic stress is suspected. The following conditions may warrant this test:

  • Strenuous Exercise Elevated lactate levels can occur following intense physical activity, indicating the body’s shift to anaerobic metabolism.
  • Heart Failure In patients with heart failure, lactate levels may rise due to inadequate oxygen delivery to tissues.
  • Severe Infection (Sepsis) Sepsis can lead to increased lactate production as the body responds to systemic infection and inflammation.
  • Shock States Conditions such as cardiogenic shock and hypovolemic shock can result in elevated lactate due to impaired tissue perfusion and oxygenation.
  • Liver Disease Liver dysfunction can affect lactate clearance, leading to elevated levels in the bloodstream.

2. Procedure

The procedure for measuring lactate levels involves several key steps, which are outlined below:

  • Step 1: Sample Collection A blood sample is obtained through venipuncture, where a needle is inserted into a vein to draw blood. This step is critical as it ensures that the sample is representative of the patient's current metabolic state. In cases where cerebrospinal fluid (CSF) is required, a lumbar puncture is performed to collect the fluid from the spinal canal.
  • Step 2: Sample Handling Once the blood or CSF sample is collected, it must be handled and processed promptly to prevent degradation of lactate levels. This may involve placing the sample in appropriate containers and ensuring it is transported to the laboratory under suitable conditions.
  • Step 3: Laboratory Analysis The lactate levels in the collected samples are measured using enzymatic methodology. This technique involves specific chemical reactions that quantify the amount of lactate present in the sample, providing accurate results for clinical interpretation.

3. Post-Procedure

After the lactate testing procedure, there are generally no specific post-procedure care requirements for the patient, especially following venipuncture. Patients may experience minor discomfort or bruising at the site of blood draw, which typically resolves on its own. If a lumbar puncture was performed, patients may be monitored for any potential complications, such as headache or infection at the puncture site. It is important for healthcare providers to communicate the results of the lactate test to the patient and discuss any necessary follow-up actions based on the findings.

Short Descr ASSAY OF LACTIC ACID
Medium Descr ASSAY OF LACTATE
Long Descr Lactate (lactic acid)
Status Code Statutory Exclusion (from MPFS, may be paid under other methodologies)
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 9 - Not Applicable
Multiple Procedures (51) 9 - Concept does not apply.
Bilateral Surgery (50) 9 - Concept does not apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 9 - Concept does not apply.
Co-Surgeons (62) 9 - Concept does not apply.
Team Surgery (66) 9 - Concept does not apply.
Diagnostic Imaging Family 99 - Concept Does Not Apply
CLIA Waived (QW) Yes
APC Status Indicator Conditionally packaged laboratory tests
Type of Service (TOS) 5 - Diagnostic Laboratory
Berenson-Eggers TOS (BETOS) T1H - Lab tests - other (non-Medicare fee schedule)
MUE 1
CCS Clinical Classification 233 - Laboratory - Chemistry and Hematology
26 Professional component: certain procedures are a combination of a physician or other qualified health care professional component and a technical component. when the physician or other qualified health care professional component is reported separately, the service may be identified by adding modifier 26 to the usual procedure number.
90 Reference (outside) laboratory: when laboratory procedures are performed by a party other than the treating or reporting physician or other qualified health care professional, the procedure may be identified by adding modifier 90 to the usual procedure number.
91 Repeat clinical diagnostic laboratory test: in the course of treatment of the patient, it may be necessary to repeat the same laboratory test on the same day to obtain subsequent (multiple) test results. under these circumstances, the laboratory test performed can be identified by its usual procedure number and the addition of modifier 91. note: this modifier may not be used when tests are rerun to confirm initial results; due to testing problems with specimens or equipment; or for any other reason when a normal, one-time, reportable result is all that is required. this modifier may not be used when other code(s) describe a series of test results (eg, glucose tolerance tests, evocative/suppression testing). this modifier may only be used for laboratory test(s) performed more than once on the same day on the same patient.
QW Clia waived test
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
GW Service not related to the hospice patient's terminal condition
77 Repeat procedure by another physician or other qualified health care professional: it may be necessary to indicate that a basic procedure or service was repeated by another physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 77 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
Q4 Service for ordering/referring physician qualifies as a service exemption
76 Repeat procedure or service by same physician or other qualified health care professional: it may be necessary to indicate that a procedure or service was repeated by the same physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 76 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
GA Waiver of liability statement issued as required by payer policy, individual case
GC This service has been performed in part by a resident under the direction of a teaching physician
GV Attending physician not employed or paid under arrangement by the patient's hospice provider
GY Item or service statutorily excluded, does not meet the definition of any medicare benefit or, for non-medicare insurers, is not a contract benefit
GZ Item or service expected to be denied as not reasonable and necessary
SA Nurse practitioner rendering service in collaboration with a physician
X5 Diagnostic services requested by another clinician: for reporting services by a clinician who furnishes care to the patient only as requested by another clinician or subsequent and related services requested by another clinician; this modifier is reported for patient relationships that may not be adequately captured by the above alternative categories; reporting clinician service examples include but are not limited to, the radiologist's interpretation of an imaging study requested by another clinician
XS Separate structure, a service that is distinct because it was performed on a separate organ/structure
XU Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service
Date
Action
Notes
2013-01-01 Changed Medium Descriptor changed.
Pre-1990 Added Code added.
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