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Official Description

Lactate dehydrogenase (LD), (LDH);

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 83615 refers to the laboratory test for measuring lactate dehydrogenase (LD) levels, also known as lactate dehydrogenase (LDH). This enzyme is found in various tissues throughout the body, including red blood cells (RBCs), heart, liver, pancreas, kidneys, skeletal muscle, brain, and lungs. The measurement of LDH levels is significant as it serves as a biomarker for tissue and RBC damage. Elevated levels of LDH in the blood can indicate a range of medical conditions, including stroke, myocardial infarction (heart attack), liver disease, pancreatitis, muscular dystrophy, infectious mononucleosis, hemolytic anemia, and certain tumors or cancers, such as lymphoma. Additionally, increased levels of LDH in cerebral spinal fluid (CSF) are typically associated with bacterial meningitis. In the context of pleural and pericardial fluids, LDH levels can help differentiate between exudative effusions, which are often due to infections, and transudative effusions, which are generally caused by fluid pressure issues. The test requires a blood sample, which is obtained through a venipuncture, and may also involve the collection of other body fluids such as CSF, pericardial fluid, or pleural fluid, each of which must be reported separately using appropriate codes for the procedures performed. The analysis of serum, plasma, and all body fluids is conducted using quantitative enzymatic methodology to ensure accurate measurement of LDH levels.

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