Coding Ahead
CasePilot
Medical Coding Assistant
Case2Code
Search and Code Lookup Tool
CareerCenter
Medical Coding Job Board
Log in Register free account

Need help choosing the right code?

Ask CasePilot about procedures, modifiers, bundling, and coding guidance.

Try CasePilot

Official Description

Lactogen, human placental (HPL) human chorionic somatomammotropin

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

A blood test is conducted to measure the levels of human placental lactogen (HPL), which is also known as human chorionic somatomammotropin. This polypeptide hormone is produced by the placenta and plays a crucial role in modifying the maternal metabolic state to ensure adequate nutrition for the developing fetus. The levels of HPL in the maternal bloodstream increase in correlation with the growth of the fetus and placenta, reaching their peak during the last trimester of pregnancy. Monitoring HPL levels can provide valuable insights into fetal well-being, as abnormal levels may indicate potential issues. The test involves obtaining a blood sample through a procedure known as venipuncture, which is reported separately. The serum obtained from the blood sample is then analyzed using an enzyme immunoassay, a laboratory technique that allows for the precise measurement of hormone levels in the serum.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The lactogen test is performed for several specific indications related to pregnancy and fetal health. These include:

  • Assessment of Fetal Well-Being HPL levels may be used as an indicator of the health and well-being of the fetus, helping to monitor its development during pregnancy.
  • Monitoring Maternal Metabolic Changes The test can help evaluate the metabolic adaptations occurring in the mother as pregnancy progresses, particularly in relation to fetal and placental growth.
  • Evaluation of Placental Function Abnormal HPL levels may suggest issues with placental function, which can impact fetal nutrition and growth.

2. Procedure

The procedure for measuring human placental lactogen (HPL) levels involves several key steps:

  • Step 1: Patient Preparation The patient may be instructed to follow specific guidelines prior to the blood draw, such as fasting or avoiding certain medications, although these instructions are not explicitly detailed in the provided data.
  • Step 2: Venipuncture A qualified healthcare professional performs venipuncture to obtain a blood sample. This involves inserting a needle into a vein, typically in the arm, to collect the necessary volume of blood for testing.
  • Step 3: Serum Separation After collection, the blood sample is processed to separate the serum from the cellular components. This is typically done by centrifugation, which spins the sample at high speed to facilitate separation.
  • Step 4: Enzyme Immunoassay Testing The serum is then subjected to an enzyme immunoassay, a laboratory technique that quantitatively measures the concentration of HPL in the serum. This method utilizes specific antibodies that bind to HPL, allowing for accurate detection and measurement.

3. Post-Procedure

After the blood sample is collected, there are generally no specific post-procedure care requirements mentioned. Patients may experience minor discomfort or bruising at the venipuncture site, which typically resolves quickly. Results from the HPL test are usually communicated to the healthcare provider, who will interpret the findings in the context of the patient's overall health and pregnancy status. Follow-up actions or additional testing may be recommended based on the results.

Short Descr PLACENTAL LACTOGEN
Medium Descr LACTOGEN HPL HUMAN CHORIONIC SOMATOMAMMOTROPIN
Long Descr Lactogen, human placental (HPL) human chorionic somatomammotropin
Status Code Statutory Exclusion (from MPFS, may be paid under other methodologies)
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 9 - Not Applicable
Multiple Procedures (51) 9 - Concept does not apply.
Bilateral Surgery (50) 9 - Concept does not apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 9 - Concept does not apply.
Co-Surgeons (62) 9 - Concept does not apply.
Team Surgery (66) 9 - Concept does not apply.
Diagnostic Imaging Family 99 - Concept Does Not Apply
CLIA Waived (QW) No
APC Status Indicator Conditionally packaged laboratory tests
Type of Service (TOS) 5 - Diagnostic Laboratory
Berenson-Eggers TOS (BETOS) T1H - Lab tests - other (non-Medicare fee schedule)
MUE 1
CCS Clinical Classification 233 - Laboratory - Chemistry and Hematology
90 Reference (outside) laboratory: when laboratory procedures are performed by a party other than the treating or reporting physician or other qualified health care professional, the procedure may be identified by adding modifier 90 to the usual procedure number.
Date
Action
Notes
Pre-1990 Added Code added.
CasePilot

Get instant expert-level medical coding assistance.

Ask about:
CPT Codes Guidelines Modifiers Crosswalks NCCI Edits Compliance Medicare Coverage
Example: "What is CPT code 99213?" or "Guidelines for E/M services"