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Official Description

Molecular diagnostics; mutation scanning, by physical properties (eg, single strand conformational polymorphisms [SSCP], heteroduplex, denaturing gradient gel electrophoresis [DGGE], RNA'ase A), single segment, each

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 83903 refers to a molecular diagnostic procedure that involves mutation scanning by utilizing various physical properties. This process is designed to identify specific genetic mutations within a single segment of DNA. The techniques employed in this procedure may include single strand conformational polymorphisms (SSCP), heteroduplex analysis, and denaturing gradient gel electrophoresis (DGGE), among others. These methods allow for the detection of variations in the DNA sequence that may be associated with certain diseases. By analyzing a sample of tissue, healthcare professionals can gain insights into the genetic factors that may contribute to the development of specific conditions, thereby aiding in diagnosis and potential treatment strategies. This procedure is crucial for understanding genetic predispositions and can play a significant role in personalized medicine.

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