CPT® Code 83937

The CPT® Code 83937 refers to the measurement of osteocalcin, which is a non-collagen protein produced by osteoblasts, the cells responsible for bone formation. This blood test is significant as it serves as a biomarker for bone turnover, providing valuable insights into the metabolic processes of bone health. Osteocalcin levels can be indicative of various conditions affecting bone density and strength, making it a useful tool in monitoring the effectiveness of therapeutic interventions in patients diagnosed with osteopenia or osteoporosis. Elevated levels of osteocalcin may be observed in several pathological conditions, including Paget's disease, bone cancer, fractures, acromegaly, primary hyperparathyroidism, hyperthyroidism, and renal osteodystrophy. Conversely, decreased levels of osteocalcin can occur in cases of hypoparathyroidism, hypothyroidism, and deficiencies in growth hormone. The test is performed by obtaining a blood sample through venipuncture, which is a separately reportable procedure. The serum or plasma obtained from the blood sample is then analyzed using a quantitative electrochemiluminescent immunoassay, a sensitive and specific method for measuring the concentration of osteocalcin in the blood.