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Official Description

Phenothiazine

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 84022 refers to a laboratory test that measures the levels of phenothiazine in the blood or urine. Phenothiazines are a group of medications primarily used as neuroleptic antipsychotics, which means they are often prescribed to manage psychiatric conditions such as schizophrenia and severe anxiety disorders. In addition to their antipsychotic effects, many phenothiazines also possess antihistamine and antiemetic properties, making them useful in treating nausea and allergic reactions. The measurement of phenothiazine levels is crucial for several reasons; it can help healthcare providers monitor therapeutic drug levels to ensure they are within a safe and effective range, as well as screen for potential exposure to these medications. The test involves obtaining a blood sample through a procedure known as venipuncture, which is separately reportable, and a urine specimen collected via random voiding. The analysis of these samples is typically conducted using advanced techniques such as chromatography coupled with mass spectrometry, which allows for precise quantification of the drug levels in the specimens.

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