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Official Description

Phosphorus inorganic (phosphate); urine

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 84105 refers to the laboratory test for measuring inorganic phosphorus, specifically phosphate levels in urine. Phosphate is a vital intracellular anion predominantly located in bone and soft tissue, playing a crucial role in various physiological functions. It is essential for cellular energy processes, which are particularly important for the proper functioning of nerves and muscles. Additionally, phosphate is integral to the formation and repair of bones and teeth. Abnormal phosphate levels can indicate underlying health issues; decreased levels are often associated with malnutrition and can lead to muscle weakness and neurological dysfunction. Conversely, elevated phosphate levels may suggest problems related to kidney function or parathyroid gland activity. The test for CPT® Code 84105 involves the collection of either a 24-hour urine sample or a random urine sample, which is then analyzed using quantitative spectrophotometry to determine the phosphate concentration. This method provides accurate measurements necessary for diagnosing and monitoring various medical conditions related to phosphate metabolism.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The test associated with CPT® Code 84105 is indicated for various clinical scenarios where phosphate levels in urine need to be assessed. The following conditions may warrant this test:

  • Malnutrition - To evaluate phosphate deficiency that may result from inadequate dietary intake.
  • Muscle Dysfunction - To investigate potential causes of muscle weakness or dysfunction linked to low phosphate levels.
  • Neurological Issues - To assess phosphate levels in patients presenting with neurological symptoms that may be related to phosphate imbalance.
  • Kidney Disorders - To monitor phosphate excretion in patients with suspected or known kidney dysfunction.
  • Parathyroid Gland Disorders - To evaluate phosphate metabolism in patients with suspected hyperparathyroidism or other parathyroid-related conditions.

2. Procedure

The procedure for obtaining a urine sample for CPT® Code 84105 involves specific steps to ensure accurate measurement of inorganic phosphorus levels. The following procedural steps are typically followed:

  • Sample Collection - A 24-hour urine collection may be required, where the patient collects all urine produced in a 24-hour period in a designated container. Alternatively, a random urine sample may be collected at any time during the day. Proper instructions should be provided to the patient to ensure the integrity of the sample.
  • Sample Preparation - Once the urine sample is collected, it should be properly labeled and transported to the laboratory for analysis. If a 24-hour collection is performed, the total volume of urine should be recorded, as this information is essential for interpreting the results.
  • Laboratory Analysis - In the laboratory, the urine sample is subjected to quantitative spectrophotometry, a method that measures the concentration of phosphate in the urine. This technique involves the use of light absorption to quantify the amount of phosphate present in the sample.

3. Post-Procedure

After the urine sample has been collected and analyzed, the results will be interpreted by a qualified healthcare professional. Depending on the findings, further diagnostic testing or clinical evaluation may be necessary. Patients may be advised on dietary modifications or additional treatments if abnormal phosphate levels are detected. It is important for healthcare providers to communicate the results to the patient and discuss any implications for their health, as well as any necessary follow-up actions.

Short Descr ASSAY OF URINE PHOSPHORUS
Medium Descr ASSAY OF PHOSPHORUS INORGANIC URINE
Long Descr Phosphorus inorganic (phosphate); urine
Status Code Statutory Exclusion (from MPFS, may be paid under other methodologies)
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 9 - Not Applicable
Multiple Procedures (51) 9 - Concept does not apply.
Bilateral Surgery (50) 9 - Concept does not apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 9 - Concept does not apply.
Co-Surgeons (62) 9 - Concept does not apply.
Team Surgery (66) 9 - Concept does not apply.
Diagnostic Imaging Family 99 - Concept Does Not Apply
CLIA Waived (QW) No
APC Status Indicator Conditionally packaged laboratory tests
Type of Service (TOS) 5 - Diagnostic Laboratory
Berenson-Eggers TOS (BETOS) T1H - Lab tests - other (non-Medicare fee schedule)
MUE 1
CCS Clinical Classification 233 - Laboratory - Chemistry and Hematology
90 Reference (outside) laboratory: when laboratory procedures are performed by a party other than the treating or reporting physician or other qualified health care professional, the procedure may be identified by adding modifier 90 to the usual procedure number.
Q4 Service for ordering/referring physician qualifies as a service exemption
26 Professional component: certain procedures are a combination of a physician or other qualified health care professional component and a technical component. when the physician or other qualified health care professional component is reported separately, the service may be identified by adding modifier 26 to the usual procedure number.
76 Repeat procedure or service by same physician or other qualified health care professional: it may be necessary to indicate that a procedure or service was repeated by the same physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 76 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
77 Repeat procedure by another physician or other qualified health care professional: it may be necessary to indicate that a basic procedure or service was repeated by another physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 77 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
91 Repeat clinical diagnostic laboratory test: in the course of treatment of the patient, it may be necessary to repeat the same laboratory test on the same day to obtain subsequent (multiple) test results. under these circumstances, the laboratory test performed can be identified by its usual procedure number and the addition of modifier 91. note: this modifier may not be used when tests are rerun to confirm initial results; due to testing problems with specimens or equipment; or for any other reason when a normal, one-time, reportable result is all that is required. this modifier may not be used when other code(s) describe a series of test results (eg, glucose tolerance tests, evocative/suppression testing). this modifier may only be used for laboratory test(s) performed more than once on the same day on the same patient.
GA Waiver of liability statement issued as required by payer policy, individual case
GV Attending physician not employed or paid under arrangement by the patient's hospice provider
GW Service not related to the hospice patient's terminal condition
GY Item or service statutorily excluded, does not meet the definition of any medicare benefit or, for non-medicare insurers, is not a contract benefit
Q3 Live kidney donor surgery and related services
QJ Services/items provided to a prisoner or patient in state or local custody, however the state or local government, as applicable, meets the requirements in 42 cfr 411.4 (b)
QW Clia waived test
Date
Action
Notes
2013-01-01 Changed Medium Descriptor changed.
Pre-1990 Added Code added.
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