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Official Description

Protein; electrophoretic fractionation and quantitation, serum

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 84165 refers to a laboratory test that measures the levels of proteins in serum through a process known as electrophoretic fractionation and quantitation. This test is essential for evaluating various health conditions by analyzing the protein composition in the blood. The procedure involves obtaining a blood sample, typically through venipuncture, which is a method of drawing blood from a vein. The serum, which is the liquid portion of the blood after clotting, is then subjected to electrophoresis. This technique separates proteins based on their size and charge, allowing for detailed analysis and quantification of different protein fractions. The results of this test can provide valuable insights into the presence of pathophysiologic states, including inflammation, gammopathies, and dysproteinemias. It is often performed alongside the total protein test (CPT® Code 84155) to give a comprehensive view of the protein levels and any abnormalities that may indicate underlying health issues. While this test is informative, it is important to note that there are more sensitive tests available for detecting similar disorders.

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