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Official Description

Sodium; serum, plasma or whole blood

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 84295 refers to the measurement of sodium levels in serum, plasma, or whole blood. This procedure involves obtaining a blood sample to assess the concentration of sodium, which is a crucial positively charged electrolyte in the body. Sodium plays a vital role in various physiological functions, including the regulation of fluid balance, maintenance of acid-base equilibrium, and support of normal metabolic processes. It works in conjunction with other electrolytes, such as potassium, chloride, and carbon dioxide (CO2), to ensure proper cellular function and overall homeostasis. The measurement of sodium levels is essential for screening and monitoring conditions such as hypernatremia, which is characterized by elevated sodium levels, and hyponatremia, which indicates low sodium levels. Additionally, sodium levels may be monitored in patients who are on specific medications, particularly diuretics, as these can lead to significant electrolyte imbalances. The sodium measurement is typically performed using ion-selective electrode (ISE) methodology, which provides accurate and reliable results for clinical assessment.

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