CPT® Code 84379

Official Description

Sugars (mono-, di-, and oligosaccharides); multiple quantitative, each specimen

Common Language Description

The CPT® Code 84379 refers to a laboratory test that quantitatively measures multiple types of sugars, including mono-, di-, and oligosaccharides, in various specimens such as blood, body fluids, or excrement. Sugars are categorized based on their molecular structure: monosaccharides are single sugar units like glucose, fructose, or galactose; disaccharides consist of two sugar units, examples being sucrose (composed of glucose and fructose), lactose (composed of glucose and galactose), and maltose (composed of two glucose units). The body utilizes these simple sugars as a primary energy source through oxidation. Oligosaccharides, which are chains of 3 to 10 monosaccharides, can attach to proteins and lipids, forming glycans that play significant roles in biological processes. These oligosaccharides are naturally found in plant fibers such as starch and cellulose and serve as prebiotics, promoting the growth of beneficial bacteria in the large intestine, which in turn aids in the production of short-chain fatty acids (SCFAs) and certain B vitamins. The test associated with CPT® Code 84379 is particularly useful for screening carbohydrate malabsorption disorders and identifying lysosomal storage diseases, including mannosidosis, fucosidosis, GM1 gangliosidosis, and sialic acid storage disease. It is important to note that CPT® Code 84378 is designated for the quantitative analysis of a single sugar, while CPT® Code 84379 is specifically for the quantitative assessment of multiple sugar molecules within a sample.

1. Indications

The CPT® Code 84379 is indicated for use in various clinical scenarios where the measurement of multiple sugars is necessary. This includes:

Carbohydrate Malabsorption Disorders - The test may be utilized to screen for conditions where the body is unable to properly absorb carbohydrates, leading to gastrointestinal symptoms.
Lysosomal Storage Diseases - It aids in the detection of specific lysosomal storage diseases such as mannosidosis, fucosidosis, GM1 gangliosidosis, and sialic acid storage disease, which can affect metabolism and lead to various health complications.

2. Procedure

The procedure for conducting the test associated with CPT® Code 84379 involves several key steps to ensure accurate measurement of multiple sugar molecules. These steps include:

Sample Collection - A specimen is collected from the patient, which may include blood, body fluids, or excrement, depending on the specific sugars being tested.
Preparation of the Sample - The collected specimen is prepared in a laboratory setting, which may involve centrifugation or other methods to isolate the sugars for analysis.
Quantitative Analysis - The laboratory performs quantitative testing to measure the concentration of various sugars present in the specimen. This may involve techniques such as chromatography or enzymatic assays to accurately determine the levels of mono-, di-, and oligosaccharides.
Data Interpretation - The results are analyzed and interpreted by qualified laboratory personnel, who will assess the levels of sugars in relation to normal ranges and clinical significance.

3. Post-Procedure

After the procedure associated with CPT® Code 84379, the laboratory will provide a report detailing the quantitative results of the sugar analysis. Healthcare providers will review these results to determine any necessary follow-up actions or further testing. Patients may be advised on dietary modifications or additional evaluations based on the findings, particularly if carbohydrate malabsorption or a lysosomal storage disease is suspected. It is essential for healthcare professionals to communicate the results effectively to the patient and discuss any implications for their health and treatment options.

Short Descr	SUGARS MULTIPLE QUANT
Medium Descr	SUGARS MONO DI&OLIGOS MLT QUANTITATIVE EA SPEC
Long Descr	Sugars (mono-, di-, and oligosaccharides); multiple quantitative, each specimen
Status Code	Statutory Exclusion (from MPFS, may be paid under other methodologies)
Global Days	XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC)	9 - Not Applicable
Multiple Procedures (51)	9 - Concept does not apply.
Bilateral Surgery (50)	9 - Concept does not apply.
Physician Supervisions	09 - Concept does not apply.
Assistant Surgeon (80, 82)	9 - Concept does not apply.
Co-Surgeons (62)	9 - Concept does not apply.
Team Surgery (66)	9 - Concept does not apply.
Diagnostic Imaging Family	99 - Concept Does Not Apply
CLIA Waived (QW)	No
APC Status Indicator	Conditionally packaged laboratory tests
Type of Service (TOS)	5 - Diagnostic Laboratory
Berenson-Eggers TOS (BETOS)	T1H - Lab tests - other (non-Medicare fee schedule)
MUE	1
CCS Clinical Classification	233 - Laboratory - Chemistry and Hematology