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Official Description

Urea nitrogen; quantitative

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 84520 refers to the quantitative measurement of urea nitrogen in the blood, commonly known as Blood Urea Nitrogen (BUN). This procedure involves obtaining a blood sample to determine the total level of urea nitrogen present. Urea is a waste product that is generated in the liver through a series of biochemical reactions known as the urea cycle, or Krebs-Henseleit cycle, which is primarily responsible for the metabolism of proteins. Once produced, urea enters the bloodstream and is subsequently filtered by the kidneys, where it is excreted in the urine. The measurement of BUN is crucial for assessing renal function, as it provides valuable insights into the kidneys' ability to filter waste from the blood. Additionally, BUN levels are monitored in patients with existing renal disease to evaluate the progression of their condition and the effectiveness of treatments such as dialysis. Furthermore, BUN may be assessed in individuals suffering from acute or chronic illnesses that could potentially impact renal function, making it an important diagnostic tool in various clinical scenarios. The quantification of BUN is typically performed using a laboratory technique called spectrophotometry, which allows for accurate measurement of the urea nitrogen concentration in the blood sample.

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