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The CPT® Code 84704 refers to the measurement of free beta chain human chorionic gonadotropin (hCG) levels through a blood sample. Human chorionic gonadotropin is a glycoprotein that plays a crucial role in pregnancy, being secreted by the trophoblast cells of the placenta. This hormone consists of two subunits: the alpha hCG and the beta hCG. During pregnancy, both subunits are typically elevated in the bloodstream, serving as important indicators of the body's physiological changes. The free beta chain of hCG is particularly significant, as its elevated levels during the first trimester can serve as a specific and sensitive diagnostic marker for various conditions. These include gestational trophoblastic neoplasms, such as hydatidiform mole and choriocarcinoma, as well as chromosomal abnormalities like Down syndrome and trisomy 18, and developmental issues such as neural tube defects. The testing process for free beta chain hCG involves a two-step methodology that utilizes two high-affinity monoclonal antibodies within an immunoradiometric assay (IRMA) system, ensuring accurate measurement of this important biomarker.
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The measurement of free beta chain human chorionic gonadotropin (hCG) levels is indicated for several clinical scenarios, particularly in the context of pregnancy and related conditions. The following are the specific indications for performing this test:
The procedure for measuring free beta chain hCG levels involves a systematic approach to ensure accurate results. The following steps outline the process:
After the blood sample has been collected and analyzed, the results are typically available within a specified timeframe, depending on the laboratory's processing capabilities. Patients may be advised to follow up with their healthcare provider to discuss the results and any necessary next steps. It is important to note that elevated levels of free beta chain hCG may require further diagnostic evaluation or monitoring, particularly in the context of the conditions indicated. Additionally, patients should be informed about any potential symptoms or signs that may warrant immediate medical attention following the test.
| Short Descr | HCG FREE BETACHAIN TEST | Medium Descr | GONADOTROPIN CHORIONIC HCG FREE BETA CHAIN | Long Descr | Gonadotropin, chorionic (hCG); free beta chain | Status Code | Statutory Exclusion (from MPFS, may be paid under other methodologies) | Global Days | XXX - Global Concept Does Not Apply | PC/TC Indicator (26, TC) | 9 - Not Applicable | Multiple Procedures (51) | 9 - Concept does not apply. | Bilateral Surgery (50) | 9 - Concept does not apply. | Physician Supervisions | 09 - Concept does not apply. | Assistant Surgeon (80, 82) | 9 - Concept does not apply. | Co-Surgeons (62) | 9 - Concept does not apply. | Team Surgery (66) | 9 - Concept does not apply. | Diagnostic Imaging Family | 99 - Concept Does Not Apply | CLIA Waived (QW) | No | APC Status Indicator | Conditionally packaged laboratory tests | Type of Service (TOS) | 5 - Diagnostic Laboratory | Berenson-Eggers TOS (BETOS) | T1H - Lab tests - other (non-Medicare fee schedule) | MUE | 1 | CCS Clinical Classification | 233 - Laboratory - Chemistry and Hematology |
| 90 | Reference (outside) laboratory: when laboratory procedures are performed by a party other than the treating or reporting physician or other qualified health care professional, the procedure may be identified by adding modifier 90 to the usual procedure number. | XU | Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service |
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| 2011-01-01 | Changed | Short description changed. |
| 2008-01-01 | Added | First appearance in code book in 2008. |
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