CPT® Code 85044

A manual reticulocyte count is a laboratory procedure that quantifies the number of reticulocytes, which are immature red blood cells (RBCs) that are released from the bone marrow into the bloodstream. These reticulocytes typically circulate in the peripheral blood for a duration of 1 to 2 days before they mature into fully developed red blood cells. The reticulocyte count is a critical diagnostic tool used to assess the bone marrow's response to the body's demand for red blood cells, particularly in situations where there is a suspicion of anemia or other hematological disorders. This test is particularly relevant when routine blood tests indicate a decrease in red blood cell count, hemoglobin levels, or hematocrit values. By evaluating the reticulocyte count, healthcare providers can gain insights into the underlying causes of anemia, such as deficiencies in vitamin B12 or folate, chronic kidney disease, the effects of chemotherapy, the status of bone marrow transplants, or the response to treatments involving erythropoietin or darbepoetin. The procedure involves obtaining a blood sample, which is then treated with new methylene blue dye to prepare a blood film. This film is subsequently examined under a microscope, where the reticulocytes are counted manually, providing valuable information regarding the patient's erythropoietic activity and overall hematological health.