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Official Description

Clotting; factor VIII (AHG), 1-stage

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

Clotting factor VIII is a crucial protein in the blood coagulation process, and its deficiency leads to hemophilia A, which is the most prevalent form of hemophilia. This inherited disorder is characterized by a significant reduction or absence of factor VIII, which is essential for the formation of stable blood clots. The CPT® Code 85240 specifically refers to a one-stage clotting test that measures the activity of factor VIII in the blood. This test is vital for diagnosing hemophilia A, as well as identifying acquired deficiencies that may arise from conditions such as liver disease or disseminated intravascular coagulopathy (DIC). During the testing process, a blood sample is collected from the patient, and the factor VIII activity is assessed by performing a one-stage clotting test. This involves comparing various dilutions of the patient's blood sample against a standardized set of dilutions to determine the level of factor VIII activity. The results of this test are typically expressed as a percentage, providing a clear indication of the patient's clotting ability related to factor VIII levels.

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