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Official Description

Antistreptolysin 0; titer

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 86060 refers to the laboratory test for measuring the concentration of antistreptolysin O (ASO) antibodies in a blood sample, commonly known as an ASO titer. This test is crucial for diagnosing various conditions associated with Group A Streptococcus bacteria. The presence of ASO antibodies in the bloodstream can indicate an active streptococcal infection, which may lead to complications such as bacterial endocarditis, post-streptococcal glomerulonephritis, rheumatic fever, or scarlet fever. The ASO titer is determined through various laboratory methods, including nephelometry and latex immunoturbidimetry, which are designed to quantify the level of these antibodies. The results of the ASO titer are typically reported in Todd units per milliliter, where a higher number of Todd units signifies a greater concentration of ASO antibodies, suggesting a more significant immune response to the streptococcal infection. This test is essential for clinicians to assess the patient's immune response and guide further management of streptococcal-related diseases.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The ASO titer test (CPT® Code 86060) is indicated for the following conditions:

  • Active Streptococcal Infection - The presence of ASO antibodies may indicate an ongoing infection caused by Group A Streptococcus.
  • Bacterial Endocarditis - Elevated ASO levels can suggest the involvement of streptococcal bacteria in the infection of the heart valves.
  • Post-Streptococcal Glomerulonephritis - ASO titers are used to evaluate kidney complications that may arise following a streptococcal infection.
  • Rheumatic Fever - The test helps in diagnosing rheumatic fever, a serious inflammatory condition that can develop after a streptococcal throat infection.
  • Scarlet Fever - ASO titers can assist in confirming the diagnosis of scarlet fever, which is caused by streptococcal bacteria.

2. Procedure

The procedure for obtaining an ASO titer (CPT® Code 86060) involves several key steps:

  • Step 1: Sample Collection - A blood sample is drawn from the patient, typically from a vein in the arm. This sample is essential for the subsequent analysis of ASO antibodies.
  • Step 2: Laboratory Analysis - The collected blood sample is sent to a laboratory where it undergoes testing using methods such as nephelometry or latex immunoturbidimetry. These techniques are designed to measure the concentration of ASO antibodies present in the sample.
  • Step 3: Result Interpretation - The laboratory reports the results in Todd units per milliliter. A higher number of Todd units indicates a greater concentration of ASO antibodies, which may suggest a more significant immune response to a streptococcal infection.

3. Post-Procedure

After the ASO titer test is performed, there are generally no specific post-procedure care requirements for the patient. However, it is important for healthcare providers to discuss the results with the patient once they are available. Elevated ASO titers may necessitate further clinical evaluation and management of any underlying conditions associated with streptococcal infections. Patients should be informed about the significance of the results and any potential follow-up tests or treatments that may be required based on the findings.

Short Descr ANTISTREPTOLYSIN O TITER
Medium Descr ANTISTREPTOLYSIN O TITER
Long Descr Antistreptolysin 0; titer
Status Code Statutory Exclusion (from MPFS, may be paid under other methodologies)
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 9 - Not Applicable
Multiple Procedures (51) 9 - Concept does not apply.
Bilateral Surgery (50) 9 - Concept does not apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 9 - Concept does not apply.
Co-Surgeons (62) 9 - Concept does not apply.
Team Surgery (66) 9 - Concept does not apply.
Diagnostic Imaging Family 99 - Concept Does Not Apply
CLIA Waived (QW) No
APC Status Indicator Conditionally packaged laboratory tests
Type of Service (TOS) 5 - Diagnostic Laboratory
Berenson-Eggers TOS (BETOS) T1H - Lab tests - other (non-Medicare fee schedule)
MUE 1
CCS Clinical Classification 235 - Other Laboratory
90 Reference (outside) laboratory: when laboratory procedures are performed by a party other than the treating or reporting physician or other qualified health care professional, the procedure may be identified by adding modifier 90 to the usual procedure number.
GW Service not related to the hospice patient's terminal condition
26 Professional component: certain procedures are a combination of a physician or other qualified health care professional component and a technical component. when the physician or other qualified health care professional component is reported separately, the service may be identified by adding modifier 26 to the usual procedure number.
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
91 Repeat clinical diagnostic laboratory test: in the course of treatment of the patient, it may be necessary to repeat the same laboratory test on the same day to obtain subsequent (multiple) test results. under these circumstances, the laboratory test performed can be identified by its usual procedure number and the addition of modifier 91. note: this modifier may not be used when tests are rerun to confirm initial results; due to testing problems with specimens or equipment; or for any other reason when a normal, one-time, reportable result is all that is required. this modifier may not be used when other code(s) describe a series of test results (eg, glucose tolerance tests, evocative/suppression testing). this modifier may only be used for laboratory test(s) performed more than once on the same day on the same patient.
GA Waiver of liability statement issued as required by payer policy, individual case
GV Attending physician not employed or paid under arrangement by the patient's hospice provider
GY Item or service statutorily excluded, does not meet the definition of any medicare benefit or, for non-medicare insurers, is not a contract benefit
Q4 Service for ordering/referring physician qualifies as a service exemption
Date
Action
Notes
2013-01-01 Changed Medium Descriptor changed.
2011-01-01 Changed Short description changed.
Pre-1990 Added Code added.
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