CPT® Code 86147

The CPT® Code 86147 refers to the laboratory test for cardiolipin (phospholipid) antibodies, specifically measuring each immunoglobulin (Ig) class, which includes IgA, IgG, and IgM. This test is conducted on a blood sample to identify the presence of these antibodies, which are associated with various medical conditions. The presence of cardiolipin antibodies is particularly significant in patients who have experienced unexplained venous or arterial thrombosis, thrombocytopenia (a condition characterized by low platelet counts), or fetal losses. The testing process typically involves an initial assessment, and if cardiolipin antibodies are detected, it is common practice to repeat the test approximately six weeks later. This follow-up is crucial to ascertain whether the antibodies are persistently present or merely a temporary finding, as low to moderate levels can sometimes occur due to infections or the influence of certain medications. In contrast, consistently elevated levels of these antibodies may suggest a more serious underlying issue, potentially contributing to the aforementioned conditions. Each class of cardiolipin antibody is reported separately, allowing for a detailed analysis of the patient's immune response.