CPT® Code 86320

Immunoelectrophoresis is a laboratory technique utilized to separate and characterize proteins based on their specific interactions with antibodies. This method is essential in the field of immunology and is particularly focused on the analysis of immunoglobulins, which are proteins that function as antibodies in the immune response. The procedure can be performed using various techniques, including one-dimensional and two-dimensional methods, each designed to enhance the resolution and identification of different protein components. The serum test, identified by CPT® Code 86320, is primarily employed to evaluate the levels of abnormal immunoglobulins, which may indicate the presence of certain hematological malignancies or disorders. Conditions such as multiple myeloma, chronic lymphocytic leukemia, Waldenstrom macroglobulinemia, amyloidosis, and lymphoma are often assessed through this test. Although immunoelectrophoresis has been a valuable diagnostic tool, it has largely been supplanted by immunofixation, a more advanced method that provides greater specificity in identifying abnormal proteins. It is important to note that for immunoelectrophoresis performed on other body fluids, such as cerebrospinal fluid, synovial fluid, and urine, the appropriate code to report is CPT® Code 86325.