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Immunoelectrophoresis, crossed or two-dimensional, is a sophisticated laboratory technique that combines two distinct methods: conventional electrophoretic separation and electroimmunodiffusion. In the first phase of the procedure, electrophoresis is conducted to separate proteins based on their size and charge. Following this initial separation, the protein strip is placed onto a slide that contains an agarose solution infused with specific antibodies. This agarose solution is allowed to solidify, creating a stable medium for the next step. The second phase involves performing electrophoresis again, but this time at a right angle to the original separation. This two-dimensional approach allows for a more detailed analysis of the proteins, as it enables the identification and characterization of various protein components within a sample. The technique is particularly useful in diagnosing and monitoring certain diseases by providing insights into the protein composition of biological fluids.
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Immunoelectrophoresis, crossed (2-dimensional assay) is performed for various clinical indications, particularly when there is a need to analyze and identify specific proteins in biological samples. The following conditions may warrant the use of this procedure:
The procedure for crossed immunoelectrophoresis involves several critical steps that ensure accurate separation and identification of proteins. Each step is essential for the successful execution of the assay.
After the completion of the crossed immunoelectrophoresis procedure, the slide is analyzed to interpret the results. The expected outcome includes the visualization of distinct bands that indicate the presence and concentration of specific proteins. These results are crucial for diagnosing various conditions, and further analysis may be required to confirm findings. It is important to ensure proper documentation of the results and any relevant clinical information to support the interpretation of the assay. Additionally, follow-up may be necessary based on the findings, which could include further testing or monitoring of the patient's condition.
| Short Descr | IMMUNOELECTROPHORESIS ASSAY | Medium Descr | IMMUNOELECTROPHORESIS CROSSED | Long Descr | Immunoelectrophoresis; crossed (2-dimensional assay) | Status Code | Active Code | Global Days | XXX - Global Concept Does Not Apply | PC/TC Indicator (26, TC) | 6 - Laboratory Physician Interpretation Code | Multiple Procedures (51) | 0 - No payment adjustment rules for multiple procedures apply. | Bilateral Surgery (50) | 0 - 150% payment adjustment for bilateral procedures does NOT apply. | Physician Supervisions | 09 - Concept does not apply. | Assistant Surgeon (80, 82) | 0 - Payment restriction for assistants at surgery applies to this procedure... | Co-Surgeons (62) | 0 - Co-surgeons not permitted for this procedure. | Team Surgery (66) | 0 - Team surgeons not permitted for this procedure. | Diagnostic Imaging Family | 99 - Concept Does Not Apply | CLIA Waived (QW) | No | APC Status Indicator | Conditionally packaged laboratory tests | Type of Service (TOS) | 5 - Diagnostic Laboratory | Berenson-Eggers TOS (BETOS) | T1H - Lab tests - other (non-Medicare fee schedule) | MUE | Not applicable/unspecified. | CCS Clinical Classification | 235 - Other Laboratory |
| 59 | Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25. | GA | Waiver of liability statement issued as required by payer policy, individual case |
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| 2024-12-31 | Deleted | Code Deleted. |
| Pre-1990 | Added | Code added. |
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